RECRUITINGOBSERVATIONAL
Longitudinal Study for Central Nervous System Vasculitis
About This Trial
Primary central nervous system vasculitis (CNSV) is a potentially fatal, single-organ vasculitis that often involves a spectrum of neurologic complications, including strokes, cognitive and speech impairment, visual loss, dementia, and encephalopathy. The purpose of this study is to establish a research cohort to investigate the disease process, treatments, and patient outcomes in CNSV.
Who May Be Eligible (Plain English)
Who May Qualify:
i. Diagnostic criteria for CNSV
1. The presence of an acquired and otherwise unexplained neurologic deficit
2. The presence of either classic angiographic or histopathologic features of angiitis in the CNS
3. No evidence of systemic vasculitis or any condition that could cause the angiographic or pathologic features
ii. ≥18 years of age
Who Should NOT Join This Trial:
i. Unwilling to sign willing to sign a consent form.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
i. Diagnostic criteria for CNSV
1. The presence of an acquired and otherwise unexplained neurologic deficit
2. The presence of either classic angiographic or histopathologic features of angiitis in the CNS
3. No evidence of systemic vasculitis or any condition that could cause the angiographic or pathologic features
ii. ≥18 years of age
Exclusion Criteria:
i. Unwilling to sign informed consent.
Locations (6)
Mayo Clinic
Rochester, Minnesota, United States
Cleveland Clinic
Cleveland, Ohio, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Vanderbilt University
Nashville, Tennessee, United States
St. Joseph's Healthcare
Hamilton, Canada
University of Toronto/Sinai Health
Toronto, Canada