Optimal Exercise Frequency to Reduce Liver Fat in Centrally Obese Adults With Non-Alcoholic Fatty Liver Disease

Who May Qualify: 1. Cantonese, Mandarin, or English speaking Chinese; 2. Aged 18-69; 3. Male or female; 4. Centrally obese according to the Asian-specific cut-off (waist circumference ≥90 cm for males; ≥80 cm for females) and with BMI ≥23; 5. With NAFLD (defined as \>5% intrahepatic triglycerides assessed by 1H-MRS); 6. Willing to participate in exercise training to improve NAFLD. Who Should NOT Join This Trial: 1. Regular exercise training (\>3 sessions of \>60 min of moderate-intensity exercise training weekly) in the past 6 months; 2. Medical history of cardiovascular disease, chronic pulmonary or kidney disease, heart failure, cancer, and/or liver disease except NAFLD; 3. Somatic conditions that limit exercise participation (e.g., limb loss); 4. Impaired mobility due to chronic disease (e.g., chronic arthritis/osteoarthritis, neurological, musculoskeletal, and autoimmune conditions (where your immune system attacks your own body)s); 5. Daily smoking habit; 6. Excess alcohol consumption (daily ≥20 g of alcohol for men and ≥10 g for women) in the past 1 year; 7. Consumption of certain drugs (e.g., tamoxifen and estrogen) known to be secondary causes of steatosis; 8. Surgery, therapy, or medication for obesity or weight loss in the past 6 months (e.g., gastric bypass, gastric band, sleeve gastrectomy, gastric reduction duodenal switch, or dietitian-prescribed dietary program); 9. Physical changes that considerably affect body composition and weight (e.g., anorexia nervosa, bulimia nervosa, prolonged gastrointestinal and digestive disorders) during the study period. Always talk to your doctor about whether this trial is right for you.