Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype

Who May Qualify: - Age 18-75 years - Moderate-severe OSA (defined as ODI ≥10 events/hour) via Polysomnography (PSG) or Home Sleep Apnea Study (HSAT) done based on clinical grounds - Excessively sleepy subtype determined by patient-reported symptoms - Willing to accept CPAP therapy - An elevated baseline office BP defined as ≥120 or ≥80 mmHg - Planned PAP (CPAP or bi-level PAP) treatment by treating provider Who Should NOT Join This Trial: - Recent changes (within 3 months) to BP medications among those who are on these medications - Unable to apply ABPM cuff - Current use of CPAP or other OSA treatments - Resting, awake SaO2 \<90% or use of home oxygen therapy - New York Heart Association (NYHA) categories III-IV of heart failure - Presence of Cheyne-Stokes Respiration (CSR) in sleep study identified by typical crescendo-decrescendo pattern of respiration with associated apneas and/or hypopneas in the absence of inspiratory flow limitation - Predominantly central sleep apnea (AHI≥15 events/hour, with \>50% central events \[apnea or hypopnea\]) - Life expectancy \<2 years - Pregnancy - Clinical history of chronic kidney disease (Stage 5) requiring dialysis, or renal transplant - Systolic BP \> 180 mmHg Always talk to your doctor about whether this trial is right for you.