Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin Carboxy-terminal Hydrolase L1 (UCH-L1) to Exclude Lesions Linked to Significant Traumatic Brain Injuries

Who May Qualify: - Traumatic brain injury defined by - Impact on the skull or the face AND OR - Acceleration / deceleration - Glasgow Coma Scal 13, 14 or 15 - One of the following 4 criteria: - \> 65 years treated with anti-platelet agent, - GCS \< 15 two hours after the trauma if associated intoxication (alcohol, narcotic, psychotropic), - Trauma with high kinetics (for information only: a risk mechanism (pedestrian knocked down by a motorized vehicle, ejection from a vehicle, fall from more than 3 steps (more than one meter), etc.), - Amnesia of facts \> 30 min before the trauma. - Having a blood sample taken as part of care with a delay between the clinical event and the biological sample \< 12 hours - Having a CT-scan prescription as part of the MTBI evaluation - Patient who signed an willing to sign a consent form form Who Should NOT Join This Trial: - Person not affiliated or not benefiting from a health insurance scheme. - Person under judicial protection. - Person with restrictions of freedom or subject to Articles L.3212-1 and L.3213-1, and not included in Article L.1122-8 of the French CSP - Blood collection time \> 12 hours - Subjects for which a scan would be carried out systematically, including: - GCS \<13 (moderate or severe trauma), - congenital hemostasis disorders or patient on anti-coagulant treatment, - clinical signs evoking a fracture of the vault or the base of the skull, - more than one episode of vomiting, - post-traumatic convulsion, - focal neurological deficit. - Obstacle to follow-up at D7 - Malignant melanomas Always talk to your doctor about whether this trial is right for you.