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RECRUITINGINTERVENTIONAL

Intensive Treatment Versus Standard Weekly Prolonged Exposure for Adults With Post-Traumatic Stress Disorder

Efficacy, Mechanisms of Change and Cost Effectiveness of Intensive Exposure-based Treatment for PTSD: a Randomized Controlled Trial

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this clinical trial is to compare a novel, massed treatment format of prolonged exposure to gold standard trauma focused cognitive behavioral therapy (weekly delivered prolonged exposure) for post-traumatic stress disorder. The objective with this study is to investigate efficacy, mechanisms of change and cost effectiveness of intensive prolonged exposure (I-PE) in regular Swedish psychiatric care. Adult patients with post-traumatic stress disorder will be randomly assigned to receive either gold standard prolonged exposure weekly for 15 weeks or 5 days of intensive treatment with the addition of three booster sessions dispersed 1, 2 and 4 weeks after completion of the massed treatment period.

Who May Be Eligible (Plain English)

Who May Qualify: - 18 years of age or above, - Primary PTSD diagnosis - Fluent in Swedish - Sign willing to sign a consent form - Able to attend either I-PE or 15 weekly sessions of PE Who Should NOT Join This Trial: - Initiation or adjustment of any psychotropic medication within the last 4 weeks prior to commencement of treatment - Serious mental health symptoms, such as mania, psychosis, alcohol, or substance use disorders or current suicide risk warranting immediate clinical attention - Ongoing evidence-based trauma-focused psychological treatment - Ongoing trauma-related threat (e.g. living with a violent spouse) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * 18 years of age or above, * Primary PTSD diagnosis * Fluent in Swedish * Sign informed consent * Able to attend either I-PE or 15 weekly sessions of PE Exclusion Criteria: * Initiation or adjustment of any psychotropic medication within the last 4 weeks prior to commencement of treatment * Serious mental health symptoms, such as mania, psychosis, alcohol, or substance use disorders or current suicide risk warranting immediate clinical attention * Ongoing evidence-based trauma-focused psychological treatment * Ongoing trauma-related threat (e.g. living with a violent spouse)

Treatments Being Tested

BEHAVIORAL

Intensive treatment with prolonged exposure

Intensive treatment with prolonged exposure

BEHAVIORAL

Weekly delivered prolonged exposure

Weekly delivered prolonged exposure sessions for 15 weeks

Locations (1)

Traumaprogrammet, Psykiatri Sydväst
Stockholm, Sweden