RECRUITINGINTERVENTIONAL
Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac Arrest
About This Trial
Out-of-hospital cardiac arrest (OHCA) has multiple etiologies. In the absence of ST-elevation myocardial infarction, percutaneous coronary intervention (PCI) is delayed. This study aims to determine the diagnostic accuracy of Coronary Calcium Score (CCS) and Coronary CT Angiogram (CCTA) to rule out a coronary artery disease (CAD) in the first days after an OHCA.
Who May Be Eligible (Plain English)
Inclusion criteria :
- Patients hospitalized in intensive care unit after a resuscitated out-of-hospital cardiac arrest
- No obvious cause for sudden death on anamnestic information, CT brain and CT pulmonary angiogram.
- Absence of ST elevation myocardial infarction
Non-inclusion criteria :
- In-hospital cardiac arrest
- Refractory cardiac arrest
- Indication of immediate coronary angiography
- ST-elevation myocardial infarction or unknown left bundle branch block
- Dynamic or presumably new contiguous ST/T-segment changes
- Cardiogenic shock
- Life-threatening arrhythmias
- Coronary artery bypass graft
- Pregnancy
- Multiple organ failure syndrome
- Know severe chronic kidney disease (GFR \<30mL/min/1,73m²)
Exclusion criteria :
- During the Coronary computerized tomographic angiogram :
- Haemodynamic instability requiring high dose of vasopressors (\>1µg/kg/min of Norepinephrine)
- Non sinusal cardiac rhythm
- KDIGO 1 Acute kidney injury
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion criteria :
* Patients hospitalized in intensive care unit after a resuscitated out-of-hospital cardiac arrest
* No obvious cause for sudden death on anamnestic information, CT brain and CT pulmonary angiogram.
* Absence of ST elevation myocardial infarction
Non-inclusion criteria :
* In-hospital cardiac arrest
* Refractory cardiac arrest
* Indication of immediate coronary angiography
* ST-elevation myocardial infarction or unknown left bundle branch block
* Dynamic or presumably new contiguous ST/T-segment changes
* Cardiogenic shock
* Life-threatening arrhythmias
* Coronary artery bypass graft
* Pregnancy
* Multiple organ failure syndrome
* Know severe chronic kidney disease (GFR \<30mL/min/1,73m²)
Exclusion criteria :
* During the Coronary computerized tomographic angiogram :
* Haemodynamic instability requiring high dose of vasopressors (\>1µg/kg/min of Norepinephrine)
* Non sinusal cardiac rhythm
* KDIGO 1 Acute kidney injury
Treatments Being Tested
OTHER
Coronary Calcium Score and Coronary CT angiogram
Introduction of early Coronary CT angiogram and Coronary Calcium Score in the first days after a resuscitated out-of-hospital cardiac arrest.
Locations (1)
Damien JOLLY
Reims, France