RECRUITINGINTERVENTIONAL
Coronary Computed Tomography AngioGraphy Prior to Catheter Ablation in Patients With Atrial FIBrillation
About This Trial
The purpose of this randomized, controlled trial is to investigate whether coronary computed tomography (CT) angiography prior to catheter ablation and derived treatment (medical anti-ischemic and multimodality treatment and/or mechanical revascularization) can improve clinical outcomes in patients with atrial fibrillation undergoing catheter ablation. A sub-study will investigate the effect of different ablation strategies on clinical outcomes in patients with atrial fibrillation undergoing catheter ablation.
Who May Be Eligible (Plain English)
Who May Qualify:
- Age over 18 years.
- Referral for catheter ablation treatment (excluding AV-junction ablation) for atrial fibrillation (both paroxysmal and persistent atrial fibrillation) at the Department of Cardiology at Gentofte Hospital. Both first ablation and re-ablation treatments are included.
- The ability and willingness to provide written willing to sign a consent form.
Who Should NOT Join This Trial:
- Known atherosclerotic cardiovascular disease (ASCVD).
- Ongoing treatment with statins.
- Contraindications for coronary CT angiography, e.g. contrast allergy
- Recent coronary CT angiography including CAC-score without positive findings \<3 years prior to screening.
- Any surgical or medical condition, which in the opinion of the investigator, may place the patient at higher risk from his/her participation in the study, or is likely to prevent the patient from complying with the requirements of the study or completing the study.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Age over 18 years.
* Referral for catheter ablation treatment (excluding AV-junction ablation) for atrial fibrillation (both paroxysmal and persistent atrial fibrillation) at the Department of Cardiology at Gentofte Hospital. Both first ablation and re-ablation treatments are included.
* The ability and willingness to provide written informed consent.
Exclusion Criteria:
* Known atherosclerotic cardiovascular disease (ASCVD).
* Ongoing treatment with statins.
* Contraindications for coronary CT angiography, e.g. contrast allergy
* Recent coronary CT angiography including CAC-score without positive findings \<3 years prior to screening.
* Any surgical or medical condition, which in the opinion of the investigator, may place the patient at higher risk from his/her participation in the study, or is likely to prevent the patient from complying with the requirements of the study or completing the study.
Treatments Being Tested
DIAGNOSTIC_TEST
Analysis of coronary CT Angiography and CAC scoring at the time of catheter ablation
Analysis of coronary CT angiography and CAC scoring and initiation of relevant derived treatment at the time of catheter ablation.
Locations (1)
Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte
Hellerup, Capital Region, Denmark