Psychopharmacotherapy for Depressive Patients

Who May Qualify: - 19 to 65 years - Diagnostic and Statistical Manual of Mental Disorders-IV criteria for major depressive disorder by study psychiatrists - Score≥17 on Hamilton Depression Rating Scale-17 - With ability to understand the objective of the study and sign willing to sign a consent form - Initiation of an antidepressant treatment for the current episode or no psychotropics excluding sleep pills or benzodiazepines within 1 month of participation Who Should NOT Join This Trial: - Current or lifetime diagnosis of bipolar disorder, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder not otherwise specified, or other psychotic disorders - current major depressive disorder with psychotic features - History of organic psychosis, epilepsy, or seizure disorder - Current anorexia nervosa or obsessive compulsive disorder - Unstable or uncontrolled medical condition - Unable to complete the psychiatric assessment or comply with the medication regimen due to a severe physical illness - History of anticonvulsant treatment - Electroconvulsive therapy for the current depressive episode - Hospitalization for any psychiatric diagnosis except depressive disorder (e.g., alcohol/drug dependence) - severly high risk of suicide, self-harm or homicide by investigator's assessment - Pregnant or breastfeeding - lack of treatment information on the current depressive episode Always talk to your doctor about whether this trial is right for you.