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RECRUITINGOBSERVATIONAL

The Role of Inflammation in Myocardial Infarction

The Complex Role of the Inflammation Response Following an Acute Myocardial Infarction: the INFINITY (INFlammatIoN amI sTudY)

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The aim of this research is to study the prognostic role of a selected combination of cytokines and adipokines in patients with myocardial infarction, as well as to determine their role in the development of adverse cardiac remodeling.

Who May Be Eligible (Plain English)

Who May Qualify: 1. ACS (ST-ACS, NSTE-ACS, UA) referred for coronary angiography 2. Above 18 years old 3. Consent form obtained Who Should NOT Join This Trial: 1. Chronic Renal Failure (CRF) stage IV (e GFR \< 29 ml/min or creatinine \> 2 mg/dl) 2. Chronic Liver Disease (CLD) (ALT \> 2 times upper normal limit) 3. Chronic Inflammation and/or autoimmune conditions (where your immune system attacks your own body)s 4. Active Ca 5. Recent CVA (less than 1 month) 6. Recent (within 2 weeks) use of glucocorticoid drugs or immunosuppressive agents 7. Acute or chronic infection, major surgery, or trauma in the last month 8. Previous heart transplantation 9. Poor life expectancy 10. Cardiogenic shock 11. Cardiac arrest Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: 1. ACS (ST-ACS, NSTE-ACS, UA) referred for coronary angiography 2. Above 18 years old 3. Consent form obtained Exclusion Criteria: 1. Chronic Renal Failure (CRF) stage IV (e GFR \< 29 ml/min or creatinine \> 2 mg/dl) 2. Chronic Liver Disease (CLD) (ALT \> 2 times upper normal limit) 3. Chronic Inflammation and/or autoimmune diseases 4. Active Ca 5. Recent CVA (less than 1 month) 6. Recent (within 2 weeks) use of glucocorticoid drugs or immunosuppressive agents 7. Acute or chronic infection, major surgery, or trauma in the last month 8. Previous heart transplantation 9. Poor life expectancy 10. Cardiogenic shock 11. Cardiac arrest

Locations (4)

Nicosia General Hospital
Nicosia, Cyprus
1st University Department of Cardiology - AHEPA University Hospital
Thessaloniki, Greece
2nd University Department of Cardiology
Thessaloniki, Greece
3rd University Department of Cardiology
Thessaloniki, Greece