Skip to main content
TTrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor.
RECRUITINGOBSERVATIONAL

Prognostic Markers for a Better Follow-up in Head and Neck Cancer.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

To identify tumor specific DNA mutations and aberrations and to follow these in blood over time to predict treatment response/survival and secondly to correlate presence of these markers in blood to pathological parameters (LVI, Pn, WPOI and margins), radiological findings and to tumor stage.

Who May Be Eligible (Plain English)

Who May Qualify: - Patient diagnosed with head and neck cancer - Treatment includes surgery - Consent to participate Who Should NOT Join This Trial: - No consent - Age below 18 years - No surgery - No tumor material to sample Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Patient diagnosed with head and neck cancer * Treatment includes surgery * Consent to participate Exclusion Criteria: * No consent * Age below 18 years * No surgery * No tumor material to sample

Treatments Being Tested

GENETIC

DNA exome sequencing of tumor and blood

A piece from tumor and a blood sample will be collected during surgery. DNA will be extracted and presence of tumor specific mutations/aberrations will be analysed with a DNA exome seq panel. Presence of identified markers will be followed in blood samples with the same panel and these blood samples will be collected in routine follow-up during the first two years. Presence of markers over time in blood will be correlated to outcomes 1-5.

Locations (1)

Karolinska universitetssjukhuset
Stockholm, Sweden