RECRUITINGINTERVENTIONAL
Conventional Bronchoscope With BAL vs. Thin Bronchoscope With BW to Diagnose Pulmonary TB
Bronchoalveolar Lavage Using a Conventional Bronchoscope vs. Bronchial Washing Using a Thin Bronchoscope to Diagnose Pulmonary Tuberculosis: a Prospective Randomized Trial
About This Trial
This study aims to compare the diagnostic yield of bronchoalveolar lavage (BAL) using a thick conventional bronchoscope and bronchial washing (BW) using a thin bronchoscope in the diagnosis of pulmonary tuberculosis.
Who May Be Eligible (Plain English)
Who May Qualify:
- participants age \> 17 years with suspected pulmonary TB
- possible active pulmonary TB evident on chest radiography or CT scan
- negative AFB smear results (using two consecutive self-expectorated sputum)
- negative TB-PCR results (using one self-expectorated sputum)
- inability to produce self-expectorated sputum
Who Should NOT Join This Trial:
- a request for empirical TB treatment rather than bronchoscopy
- suspect pulmonary TB lesions that are difficult to target for BAL or BW (e.g., multiple discrete tiny nodules)
- contra-indication of bronchoscopy (e.g., bleeding tendency, hypoxemia requiring oxygen, or uncontrolled cardio/cerebrovascular disease)
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* participants age \> 17 years with suspected pulmonary TB
* possible active pulmonary TB evident on chest radiography or CT scan
* negative AFB smear results (using two consecutive self-expectorated sputum)
* negative TB-PCR results (using one self-expectorated sputum)
* inability to produce self-expectorated sputum
Exclusion Criteria:
* a request for empirical TB treatment rather than bronchoscopy
* suspect pulmonary TB lesions that are difficult to target for BAL or BW (e.g., multiple discrete tiny nodules)
* contra-indication of bronchoscopy (e.g., bleeding tendency, hypoxemia requiring oxygen, or uncontrolled cardio/cerebrovascular disease)
Treatments Being Tested
DEVICE
bronchial washing using a thin bronchoscope
For intervention, we plan to perform bronchial washing using a thin bronchoscope instead of bronchoalveolar lavage with the conventional thick bronchoscope to diagnose pulmonary TB.
Locations (1)
Pusan National University Hospital
Busan, South Korea