Myocardial Dysfunction Evaluation in Lower Extremity Arterial Disease Patients With Deformation Analysis

Inclusion Criteria in LEAD group: - Fontaine I-IV class symptoms - Confirmed diagnosis of LEAD Inclusion Criteria in control group: - Age 35-85 - Has to have at least of the following: hypertension, diabetes, coronary artery disease or the patient smokes Who Should NOT Join This Trial: - Age \<35 or \>85 years - BMI ≥40 kg/m² - Known heart failure in history - Any acute or chronic autoimmune or rheumatic disease - Cardiac structural disease in history: inflammatory, infiltrative diseases, nonischemic cardiomyopathies - Acute coronary syndrome in last 3 months - Moderate to severe cardiac valvular disease - Cardiac valvular disease operative/invasive treatment in history - Cardiac implantable electronic device (CIED) - Transitory ischemic attack or stroke in last 3 months - Severe COPD (GOLD C or D) - Moderate to severe asthma (according to GINA 2022 criteria) - Untreated hypertension (noninvasive blood pressure measurement ≥180/110 mmHg during recruitment) - Chronic severe kidney dysfunction (eGFR \<30 ml/min/1,73 m²) - Malignant tumor with radiation treatment to thorax, oncologic or biologic treatment in history - Chronic hematologic disease (except for anemia) - Severe liver dysfunction - Malignant tumor with \<5 years of remission - Acute or chronic infectious disease - Anemia with hemoglobin \<80 g/L Always talk to your doctor about whether this trial is right for you.