Study on the Efficacy and Safety of Conversion Therapy in Patients With Initially Unresectable Hepatocellular Carcinoma

Who May Qualify: - ≥ 18 years old, gender is not limited; - Patients with radiographically or pathologically confirmed, unresectable advanced hepatocellular carcinoma; - At least one measurable lesion according to the mRECIST criteria as the target lesion; - No prior immunotherapy, including but not limited to anti-CTLA-4, anti-PD-1, and anti-PD-L1 antibodies; - Patients with an ECOG score of 0-2 were included according to the activity status score scale developed by the Eastern Cooperative Oncology Group (ECOG) in the United States; - Child-Pugh liver function is graded as A or B. Who Should NOT Join This Trial: - Have a history of weakened immune system, or have other acquired or congenital weakened immune system diseases; - Have other malignancies; - Presence of any active autoimmune conditions (where your immune system attacks your own body) or history of autoimmune conditions (where your immune system attacks your own body) (including, but not limited to: autoimmune hepatitis, interstitial pneumonia, uveitis, enteritis, hepatitis, hypophysitis, vasculitis, nephritis, hyperthyroidism, hypothyroidism), or known history of allogeneic organ transplantation or allogeneic hematopoietic stem cell transplantation, or other patients who are considered by the investigator to have an impact on study treatment; - Long-term heavy use of corticosteroids or other immunomodulators; - Serious illness in combination with other systems; - Received a live or attenuated vaccine within 30 days prior to the first dose, or plans to receive a live or attenuated vaccine during the study, excluding the new crown vaccine; - Known human weakened immune system virus (HIV) infection; - Have participated in other therapeutic clinical studies; - Incomplete clinical data. Always talk to your doctor about whether this trial is right for you.