RECRUITINGOBSERVATIONAL
Clinical Biomarker of Paclitaxel-induced Peripheral Neuropathy
About This Trial
Investigation of which patients treated with paclitaxel have an increased risk of developing peripheral neuropathy.
Who May Be Eligible (Plain English)
Who May Qualify:
- Age \> 18 years
- Willing to give willing to sign a consent form
- Scheduled to receive neo-adjuvant or adjuvant paclitaxel treatment
- Able to speak and understand Danish
- Diagnosed with breast cancer
- Paclitaxel naïve patients
Who Should NOT Join This Trial:
- Neurodegenerative diseases (e.g., neuropathy from another cause, previous apoplexy, disc herniation
- Type 1 or 2 diabetes
- Pregnant
- Breastfeeding
- Relapse of cancer diagnosis
- Diagnosed with human weakened immune system virus (HIV)
- Participation in other clinical trials where the dose of paclitaxel is changed, or the aim is to prevent neuropathic pain or decrease NFL level (except if the intervention is to use cooling gloves).
- Previous treatment with neurotoxic chemotherapy
- Chronic pain from another cause
- Metastatic cancer
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Age \> 18 years
* Willing to give informed consent
* Scheduled to receive neo-adjuvant or adjuvant paclitaxel treatment
* Able to speak and understand Danish
* Diagnosed with breast cancer
* Paclitaxel naïve patients
Exclusion Criteria:
* Neurodegenerative diseases (e.g., neuropathy from another cause, previous apoplexy, disc herniation
* Type 1 or 2 diabetes
* Pregnant
* Breastfeeding
* Relapse of cancer diagnosis
* Diagnosed with human immunodeficiency virus (HIV)
* Participation in other clinical trials where the dose of paclitaxel is changed, or the aim is to prevent neuropathic pain or decrease NFL level (except if the intervention is to use cooling gloves).
* Previous treatment with neurotoxic chemotherapy
* Chronic pain from another cause
* Metastatic cancer
Treatments Being Tested
OTHER
No intervention
No intervention
Locations (3)
Odense University Hospital
Odense, Denmark
University Hospital of Southern Denmark, Sønderborg
Sønderborg, Denmark
University Hospital of Southern Denmark, Vejle
Vejle, Denmark