A Clinical Study of SHR-9539 in Patients With Multiple Myeloma

Who May Qualify: 1. Age ≥ 18 years on day of signing the willing to sign a consent form Form; 2. Have a performance status of 0 or 1 on the Eastern Cooperative Oncology Group (ECOG) Performance Status Scale； 3. Documented initial diagnosis of multiple myeloma according to IMWG diagnostic criteria ； 4. Have a expected to live at least 3 months； 5. Male and female subjects with fertility must agree to use efficient contraceptive measures with their partners within 3 months after the last administration of the test drug from the time of signing the willing to sign a consent form form, and have no fertility plan and avoid donating sperm / eggs. The pregnancy test during the screening period must be negative. Who Should NOT Join This Trial: 1. Central nervous system (CNS) involvement of MM； 2. Diagnosis of amyloidosis, plasma cell leukemia, Wahl's macroglobulinemia, or POEMS syndrome; 3. Prior Grade 3 or higher CRS (Per ASTCT standards) related to any T cell redirection (eg, CD-3 redirection technology or CAR-T cell therapy). 4. Have other factors that may force the termination of the study, e.g., non-compliance with the protocol, other serious illnesses (including psychiatric illnesses) that require comorbid treatment, serious laboratory abnormalities, associated family or social factors, which would affect the safety of the subjects or the collection of data and samples, as determined by the investigator. Always talk to your doctor about whether this trial is right for you.