RECRUITINGINTERVENTIONAL
68Ga-C1 PET/ CT Imaging in Clear Cell Renal Cell Carcinoma
Evaluation of Diagnostic Value of 68Ga-C1 PET/ CT Imaging in Clear Cell Renal Cell Carcinoma
About This Trial
The goal of this clinical trial is to evaluate the diagnostic value of CAIX protein specific probe 68Ga-C1 in PET/CT imaging in clear cell renal cell carcinoma patients. It will also learn about the safety, tolerability and radiation dosimetry of 68Ga-C1. Researchers will compare the diagnostic value of 68Ga-C1 PET/CT and 18F-FDG PET/CT in Chinese patients with indeterminate renal masses or confirmed clear cell renal cell carcinoma.
Who May Be Eligible (Plain English)
Who May Qualify:
1. Signed written willing to sign a consent form;
2. Age ≥18;
3. Patients with confirmed or suspected clear cell renal cell carcinoma;
4. Expected survival ≥6 months.
Who Should NOT Join This Trial:
1. Renal mass is known to be a metastasis of another primary tumor;
2. Have other malignancies that require treatment;
3. Have received chemotherapy, radiotherapy, or immunotherapy within 4 weeks;
4. Renal insufficiency with glomerular filtration rate (GFR) ≤ 60 mL/min/1.73 m²;
5. Pregnant and lactating women or female patients plan to become pregnant within 6 months;
6. Uncontrolled psychiatric disorders;
7. Vulnerable population (e.g., being in detention) or have a serious non-malignant disease (e.g., infectious disease, autoimmune conditions (where your immune system attacks your own body), or metabolic disease).
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
1. Signed written informed consent;
2. Age ≥18;
3. Patients with confirmed or suspected clear cell renal cell carcinoma;
4. Expected survival ≥6 months.
Exclusion Criteria:
1. Renal mass is known to be a metastasis of another primary tumor;
2. Have other malignancies that require treatment;
3. Have received chemotherapy, radiotherapy, or immunotherapy within 4 weeks;
4. Renal insufficiency with glomerular filtration rate (GFR) ≤ 60 mL/min/1.73 m²;
5. Pregnant and lactating women or female patients plan to become pregnant within 6 months;
6. Uncontrolled psychiatric disorders;
7. Vulnerable population (e.g., being in detention) or have a serious non-malignant disease (e.g., infectious disease, autoimmune disease, or metabolic disease).
Treatments Being Tested
DRUG
68Ga-C1
68Ga-C1 is injected intravenously with a dose of 0.05-0.10 mCi/kg
Locations (1)
Peking University First Hospital
Beijing, Beijing Municipality, China