Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Who May Qualify: - Male or female participants, 6 to \<12 years of age at screening - HeFH diagnosed either by genetic testing or on phenotypic criteria - Fasting LDL-C \>130 mg/dL (3.4 mmol/L) at screening - For participants 8 to \<12 years, on an optimal dose of statin (investigator's discretion) unless statin intolerant, with or without other lipid-lowering therapy (e.g. ezetimibe). For participants \<8 years, the use of background lipid-lowering treatment is based on investigator's discretion. - Participants on lipid-lowering therapies (such as statin and/or e.g. ezetimibe) must be on a stable dose for ≥30 days before screening with no planned medication or dose changes during study participation. Who Should NOT Join This Trial: - Previous treatment (within 90 days of screening) with monoclonal antibodies directed towards PCSK9 - Secondary hypercholesterolemia, e.g. hypothyroidism or nephrotic syndrome - Homozygous familial hypercholesterolemia (HoFH) - Body weight \<16 kg at the screening and/or randomization (Day 1) visit - Active liver disease defined as any known current infectious, neoplastic, or metabolic pathology of the liver or unexplained alanine aminotransferase (ALT), aspartate aminotransferase (AST) elevation \>3x ULN, or total bilirubin elevation \>2x ULN (except patients with Gilbert's syndrome) - Pregnant or nursing females - Recent and/or planned use of other investigational medicinal products or devices Always talk to your doctor about whether this trial is right for you.