RECRUITINGINTERVENTIONAL
Evaluating Modulation Effects of Burst Stimulation Patterns Using SEEG
About This Trial
The study aims to evaluate modulation effects of burst stimulation patterns via SEEG.
Who May Be Eligible (Plain English)
Who May Qualify:
- Drug-resistant focal epilepsy
- Justified SEEG exploration in the context of presurgical assessment of epilepsy
- Subjects will be a part of the epilepsy-monitoring unit for long-term SEEG recordings and analysis
- Written non-opposition to study participation
Who Should NOT Join This Trial:
- Pregnant women (Contraindication to SEEG exploration)
- Psychiatric disorders
- History of psychotic disorders
- History of cranial trauma serious (according to the classification), previous or evolutionary other neurological pathology
- Subjects that experience surgical complications during the implant procedure will be excluded from the study
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Drug-resistant focal epilepsy
* Justified SEEG exploration in the context of presurgical assessment of epilepsy
* Subjects will be a part of the epilepsy-monitoring unit for long-term SEEG recordings and analysis
* Written non-opposition to study participation
Exclusion Criteria:
* Pregnant women (Contraindication to SEEG exploration)
* Psychiatric disorders
* History of psychotic disorders
* History of cranial trauma serious (according to the classification), previous or evolutionary other neurological pathology
* Subjects that experience surgical complications during the implant procedure will be excluded from the study
Treatments Being Tested
OTHER
Single-pulse stimulation
Investigators use single-pulse electrical stimulations at 1Hz to elicit cortico-cortical evoked potentials
OTHER
Paired-pulse stimulation
The repetitive delivery of pairs of stimulation pulses is DES patten with a 5-50 ms interval between each pulse, constitutes repetitive paired-pulse stimulation.
OTHER
Stepwise frequency stimulation
Stepwise incremental stimulation ranging from 5 Hz to 145 Hz following a cyclic pattern.
OTHER
Burst stimulation
Burst stimulation pattern consisting of short bursts delivered once a second and an intraburst frequency of 50 Hz, 100 Hz, 150 Hz, 175 Hz and 200 Hz
Locations (1)
Xuanwu Hospital,Capital Medical University
Beijing, Beijing Municipality, China