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RECRUITINGINTERVENTIONAL

Evaluating Modulation Effects of Burst Stimulation Patterns Using SEEG

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The study aims to evaluate modulation effects of burst stimulation patterns via SEEG.

Who May Be Eligible (Plain English)

Who May Qualify: - Drug-resistant focal epilepsy - Justified SEEG exploration in the context of presurgical assessment of epilepsy - Subjects will be a part of the epilepsy-monitoring unit for long-term SEEG recordings and analysis - Written non-opposition to study participation Who Should NOT Join This Trial: - Pregnant women (Contraindication to SEEG exploration) - Psychiatric disorders - History of psychotic disorders - History of cranial trauma serious (according to the classification), previous or evolutionary other neurological pathology - Subjects that experience surgical complications during the implant procedure will be excluded from the study Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Drug-resistant focal epilepsy * Justified SEEG exploration in the context of presurgical assessment of epilepsy * Subjects will be a part of the epilepsy-monitoring unit for long-term SEEG recordings and analysis * Written non-opposition to study participation Exclusion Criteria: * Pregnant women (Contraindication to SEEG exploration) * Psychiatric disorders * History of psychotic disorders * History of cranial trauma serious (according to the classification), previous or evolutionary other neurological pathology * Subjects that experience surgical complications during the implant procedure will be excluded from the study

Treatments Being Tested

OTHER

Single-pulse stimulation

Investigators use single-pulse electrical stimulations at 1Hz to elicit cortico-cortical evoked potentials

OTHER

Paired-pulse stimulation

The repetitive delivery of pairs of stimulation pulses is DES patten with a 5-50 ms interval between each pulse, constitutes repetitive paired-pulse stimulation.

OTHER

Stepwise frequency stimulation

Stepwise incremental stimulation ranging from 5 Hz to 145 Hz following a cyclic pattern.

OTHER

Burst stimulation

Burst stimulation pattern consisting of short bursts delivered once a second and an intraburst frequency of 50 Hz, 100 Hz, 150 Hz, 175 Hz and 200 Hz

Locations (1)

Xuanwu Hospital,Capital Medical University
Beijing, Beijing Municipality, China