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RECRUITINGINTERVENTIONAL

Individual Factors of CBT Underlying Success

Contributions of Self-Focused Attention to Early Warning Indicators of Cognitive Behavioral Therapy Non-Response

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The purpose of this study is to understand why some individuals respond fully to cognitive behavioral therapy and others do not, based on multiple sources of data such as neural, neurocognitive, clinical, and self-report data.

Who May Be Eligible (Plain English)

Who May Qualify: Clinical sample (N=110): 1. Men and women, age 18-45 2. Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV 3. Fluent in English and willing to provide willing to sign a consent form. Control sample (N=50): 1. Men and women, age 18-45 2. No current or lifetime history of psychiatric disorders, as assessed using the SCID-5-RV 3. Meet criteria for low levels of anxiety (GAD-7 score of \<8) and depression (PHQ-9 score \<10) 4. Fluent in English and willing to provide willing to sign a consent form Who Should NOT Join This Trial: All groups: 1. Score \< 80 based on WRAT5 Word Reading Subtest 2. fMRI contraindications (e.g., electronic medical devices such as pacemakers, implanted defibrillators, etc.; metal implants not approved for MRI; pregnancy; claustrophobia) 2\. Active suicidal or homicidal ideation, or any features requiring a higher level of care 3. Lifetime history of manic or hypomanic episode, psychotic symptoms, traumatic brain injury, neurological disorder, pervasive developmental disorder, or attention deficit-hyperactivity disorder; active alcohol or substance use disorder in the past 6 months 4. Current use of psychotropic medications, except antidepressants taken at a stable dose for 3 months prior to study baseline 5. Previous CBT non-responder or current CBT Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: Clinical sample (N=110): 1. Men and women, age 18-45 2. Treatment-seeking individuals who meet criteria for a primary DSM-5 diagnosis of primary social anxiety disorder (SAD) or body dysmorphic disorder (BDD) based on the SCID-5-RV 3. Fluent in English and willing to provide informed consent. Control sample (N=50): 1. Men and women, age 18-45 2. No current or lifetime history of psychiatric disorders, as assessed using the SCID-5-RV 3. Meet criteria for low levels of anxiety (GAD-7 score of \<8) and depression (PHQ-9 score \<10) 4. Fluent in English and willing to provide informed consent Exclusion Criteria: All groups: 1. Score \< 80 based on WRAT5 Word Reading Subtest 2. fMRI contraindications (e.g., electronic medical devices such as pacemakers, implanted defibrillators, etc.; metal implants not approved for MRI; pregnancy; claustrophobia) 2\. Active suicidal or homicidal ideation, or any features requiring a higher level of care 3. Lifetime history of manic or hypomanic episode, psychotic symptoms, traumatic brain injury, neurological disorder, pervasive developmental disorder, or attention deficit-hyperactivity disorder; active alcohol or substance use disorder in the past 6 months 4. Current use of psychotropic medications, except antidepressants taken at a stable dose for 3 months prior to study baseline 5. Previous CBT non-responder or current CBT

Treatments Being Tested

BEHAVIORAL

Cognitive Behavioral Therapy

Twelve weekly sessions of individual cognitive behavioral therapy

Locations (1)

University of Washington
Seattle, Washington, United States