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RECRUITINGOBSERVATIONAL

PeRfusiOn Post tHrombEcTomy (PROPHET)

PeRfusiOn Post tHrombEcTomy (PROPHET) A Prospective Observational Cohort Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Endovascular mechanical thrombectomy is the standard of care for treating patients with a large-vessel occlusion acute ischemic stroke. However, in more than half of these patients, remaining distal vessel occlusions limit the benefit of this therapy. Currently the detection of residual vessel occlusions and the decision for further treatment by the operator is based on the 2D digital subtraction angiography (DSA) images. However, this technique has several limitations. Recently, a new imaging technique, with the possibility to acquire 3D time-resolved perfusion images directly in the operating room was introduced (the flat-panel detector computed tomography perfusion imaging, FDCTP). It can overcome the spatial limitations of 2D DSA, but the details on clinical validation and utility of FDCTP are currently lacking.

Who May Be Eligible (Plain English)

Who May Qualify: - willing to sign a consent form as documented by a signature - The patients received mechanical thrombectomy or there was the intention to perform endovascular treatment, but only diagnostic angiography was performed. - Patients received FDCTP as clinically indicated by the treating physician. Who Should NOT Join This Trial: - Inability to give consent due to insufficient knowledge of the project language - Inability to follow the clinically indicated visit at 90 days after the index stroke (e.g. patients living abroad). Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Informed consent as documented by a signature * The patients received mechanical thrombectomy or there was the intention to perform endovascular treatment, but only diagnostic angiography was performed. * Patients received FDCTP as clinically indicated by the treating physician. Exclusion Criteria: * Inability to give consent due to insufficient knowledge of the project language * Inability to follow the clinically indicated visit at 90 days after the index stroke (e.g. patients living abroad).

Locations (2)

University Hospital Basel
Basel, Switzerland
University Hospital Bern
Bern, Switzerland