RECRUITINGINTERVENTIONAL
Probiotics in Pulmonaty Rehabilitation for COPD
Probiotics in the Management of Pulmonary Rehabilitation for COPD: A Randomized Controlled Trial
About This Trial
This study aims to investigate various aspects of patients with chronic respiratory diseases undergoing pulmonary rehabilitation supplemented with probiotics. The focus will be on clinical physiological responses, functional performance, respiratory status assessments, nutritional status evaluations, body composition analyses, and biochemical blood parameters, with a primary emphasis on the anti-inflammatory response.
Who May Be Eligible (Plain English)
Who May Qualify:
- Willing to sign a written willing to sign a consent form form.
- Diagnosed with pre-COPD or COPD stage I-IV according to the 2023 GOLD guidelines.
- Undergoing pulmonary rehabilitation therapy for more than three months.
Who Should NOT Join This Trial:
- Under 18 years old.
- Diagnosed with neuromuscular diseases.
- Experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months.
- Unable to cooperate with cardiopulmonary exercise testing.
- Has other diseases or behavioral restrictions preventing participation in exercise training for over one year.
- Assessed by a physician to have severe malnutrition or a significantly low BMI.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Willing to sign a written informed consent form.
* Diagnosed with pre-COPD or COPD stage I-IV according to the 2023 GOLD guidelines.
* Undergoing pulmonary rehabilitation therapy for more than three months.
Exclusion Criteria:
* Under 18 years old.
* Diagnosed with neuromuscular diseases.
* Experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months.
* Unable to cooperate with cardiopulmonary exercise testing.
* Has other diseases or behavioral restrictions preventing participation in exercise training for over one year.
* Assessed by a physician to have severe malnutrition or a significantly low BMI.
Treatments Being Tested
OTHER
probiotic supplementation intervention
probiotic supplementation will be administered, while participants continue undergoing routine pulmonary rehabilitation therapy
OTHER
standard pulmonnary rehabilitation
undergo routine pulmonary rehabilitation without probiotics intervention
Locations (1)
Fu Jen Catholic University Hospital, Fu Jen Catholic University
New Taipei City, Taiwan