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RECRUITINGPhase 4INTERVENTIONAL

Optimal PERioperative Antiplatelet Therapy Investigation ON Abdominal Surgery After Coronary Stent Implantation

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The purpose of this study is to evaluate the impact of perioperative aspirin continuation on clinical outcomes in patients with a history of coronary stent implantation who are scheduled for abdominal surgery.

Who May Be Eligible (Plain English)

Who May Qualify: - Patients with a history of coronary stenting and scheduled for abdominal surgery - Patients on a single antiplatelet agent Who Should NOT Join This Trial: - Patients on dual antiplatelet therapy (DAPT) - Patients on anticoagulation therapy - Patients with a history of stent thrombosis - Patients with CHADS2 score \>= 5 - Patients at extremely high risk of bleeding and unable to continue preoperative aspirin - Patients incapable of consent, including those under 20 years of age - Other patients for whom either discontinuation or continuation of antiplatelet agents is deemed inappropriate by the attending physician Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Patients with a history of coronary stenting and scheduled for abdominal surgery * Patients on a single antiplatelet agent Exclusion Criteria: * Patients on dual antiplatelet therapy (DAPT) * Patients on anticoagulation therapy * Patients with a history of stent thrombosis * Patients with CHADS2 score \>= 5 * Patients at extremely high risk of bleeding and unable to continue preoperative aspirin * Patients incapable of consent, including those under 20 years of age * Other patients for whom either discontinuation or continuation of antiplatelet agents is deemed inappropriate by the attending physician

Treatments Being Tested

DRUG

Aspirin

perioperative aspirin continuation

DRUG

Aspirin interruption

Aspirin interruption 5-7 days before surgery

Locations (1)

Kyoto University Hospital
Kyoto, Japan