RECRUITINGOBSERVATIONAL
Exosomes Proteomic for Sjogren's Syndrome and Dry Eye Syndrome
Systemic Proteomic Analysis of Plasma Exosomes to Explore the Immunomodulation Reflected to Sjogren's Syndrome and Dry Eye Syndrome
About This Trial
By analyzing the differential proteins in exosomes, this study aims to understand the pathological mechanisms of SJS and DES, identify potential diagnostic and therapeutic methods, and advance the diagnosis and treatment of these diseases.
Who May Be Eligible (Plain English)
Dry eye syndrome
Who May Qualify: aged between 20 and 75 years Schirmer's test less than 10 mm/5 min Who Should NOT Join This Trial: Pregnancy With eye inflammation or infectious eye disease Accepted operation of eye Sjögren's syndrome
Who May Qualify: primary or secondary SS aged between 20 and 75 years fulfilled the 2002 American-European Consensus Criteria for SS (AECG) had no abnormal findings of immune, liver, kidney, or blood function evaluations.
Who Should NOT Join This Trial: a history of alcohol abuse, diabetes mellitus, or major life-threatening condition pregnancy or breastfeeding steroid pulse therapy within three months prior to the commencement of our study.
non AIDDES Healthy Controls
Who May Qualify: aged between 20 and 75 years without any Chronic disease Who Should NOT Join This Trial: any Sjögren's syndrome or Dry eye syndrome.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Dry eye syndrome
Inclusion Criteria: aged between 20 and 75 years Schirmer's test less than 10 mm/5 min Exclusion Criteria: Pregnancy With eye inflammation or infectious eye disease Accepted operation of eye Sjögren's syndrome
Inclusion Criteria: primary or secondary SS aged between 20 and 75 years fulfilled the 2002 American-European Consensus Criteria for SS (AECG) had no abnormal findings of immune, liver, kidney, or blood function evaluations.
Exclusion Criteria: a history of alcohol abuse, diabetes mellitus, or major life-threatening condition pregnancy or breastfeeding steroid pulse therapy within three months prior to the commencement of our study.
non AIDDES Healthy Controls
Inclusion Criteria: aged between 20 and 75 years without any Chronic disease Exclusion Criteria: any Sjögren's syndrome or Dry eye syndrome.
Treatments Being Tested
OTHER
acupuncture GB20 or GB20 plus BL2
acupuncture at acupoint GB20 or GB20 plus BL2 twice a week 8 weeks for efficacy evaluation.
DRUG
Chinese herbal tea TBDESJS
Chinese herbal tea TBDESJS 8 weeks on Nourishing Yin and Moistening Dryness the ocular dryness evaluation.
Locations (1)
Ching-Mao
Taipei, Taiwan, Taiwan