RECRUITINGOBSERVATIONAL
Diagnosis, Treatment, and Outcome Assessment of Septic Cardiomyopathy Using an Integrated Mathematical Model
Use of an Integrated Mathematical Model for the Diagnosis, Treatment and Outcome Assessment of Septic Cardiomyopathy
About This Trial
The goal of this observational study is to evaluate whether a new integrated mathematical model can improve the accuracy of diagnosing septic cardiomyopathy and predicting clinical outcomes in adult patients with suspected septic cardiomyopathy. The study aims to determine whether the integrated mathematical model enhances diagnostic accuracy and improves the prediction of clinical outcomes in these patients.
Who May Be Eligible (Plain English)
Who May Qualify:
- Age 18 years or older;
- Sepsis according to SEPSIS-3 criteria:
- Suspected/confirmed infection and
- SOFA (Sequential Organ Failure Assessment) score ≥ 2 or qSOFA score ≥ 2;
- Septic shock according to SEPSIS-3 criteria:
- Sepsis is diagnosed and
- Vasopressor infusion is used to maintain a mean arterial pressure (MAP) ≥ 65 mmHg and
- Lactate \> 2 mmol/l;
- Cardiovascular support requirement for norepinephrine \> 0.1 mcg/kg/min infusion;
- Signed willing to sign a consent form form (ICF);
Who Should NOT Join This Trial:
- Individuals under 18 years of age;
- Has uncompensated cardiovascular disease:
- Cardiogenic shock;
- Congenital heart disease;
- Heart failure NYHA functional class IV;
- Refusal to participate in the study.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Age 18 years or older;
* Sepsis according to SEPSIS-3 criteria:
* Suspected/confirmed infection and
* SOFA (Sequential Organ Failure Assessment) score ≥ 2 or qSOFA score ≥ 2;
* Septic shock according to SEPSIS-3 criteria:
* Sepsis is diagnosed and
* Vasopressor infusion is used to maintain a mean arterial pressure (MAP) ≥ 65 mmHg and
* Lactate \> 2 mmol/l;
* Cardiovascular support requirement for norepinephrine \> 0.1 mcg/kg/min infusion;
* Signed informed consent form (ICF);
Exclusion Criteria:
* Individuals under 18 years of age;
* Has uncompensated cardiovascular disease:
* Cardiogenic shock;
* Congenital heart disease;
* Heart failure NYHA functional class IV;
* Refusal to participate in the study.
Locations (2)
Vilnius University Hospital Santaros Klinikos
Vilnius, Lithuania
University Clinical Centre of the Medical University of Warsaw
Warsaw, Poland