Efficacy of Hi-tACS for Schizophrenia Negative Symptoms

Who May Qualify: - Han Chinese population; - Age ≥ 18 years; - Education level ≥ 6 years, able to fill out questionnaires on their own, and having sufficient audiovisual level to complete the necessary examinations; - Meets DSM-5 diagnostic criteria for schizophrenia as assessed by MINI 7.0; - Residual negative symptoms, with at least one item ≥2 on the negative subscale of PANSS (N1-N7); - Taking second-generation atypical antipsychotic medication, with no medication or dosage adjustments in the last two weeks - Patients and guardians agreed to participate in the study and signed an willing to sign a consent form form. Who Should NOT Join This Trial: - Meets DSM-5 diagnostic criteria for other mental disorders; - Total score ≥19 on the PANSS positive subscales (P1-P7) ; - Severe negative symptoms that prevent the patient from completing the required assessments and interventions; - Serious physical or central nervous system disease (intracranial infection, intracranial tumor, presence of metal objects in the skull; epilepsy, seizures; history of hydrocephalus or central nervous system tumors; with implanted electronic devices; serious cardiac disease and fitted with a pacemaker, etc.); - Impaired skin integrity at the site of electrode placement or hypersensitivity to electrode gels or adhesives; - Mental retardation (Wechsler Adult Intelligence Scale WAIS \<70) and/or severe cognitive impairment (Brief Mental State Examination MMSE \<24); - Presence of vision and/or hearing problems that prevent completion of relevant tests; - Alcohol or drug abuse/dependence; - Pregnancy; - Those who have participated or are participating in other clinical studies 3 months ago; - Failure or refusal to sign the willing to sign a consent form form. Always talk to your doctor about whether this trial is right for you.