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RECRUITINGINTERVENTIONAL

Texture and Color Enhancement Imaging (TXI) for Inflammation Assessment in Patients With Inflammatory Bowel Diseases

Texture and Color Enhancement Imaging (TXI) for Real-time Prediction of Histologic Changes in Patients With Inflammatory Bowel Diseases: a Comparison of White Light Endoscopy (WLE) Versus TXI

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

In the context of the COLORIZE study, it is being tested whether the endoscopic light mode Texture and Color Enhancement Imaging (TXI) is non-inferior to the standard White Light Endoscopy (WLE) in assessing inflammatory activity in patients with Inflammatory Bowel Disease (IBD). For this purpose, ileocolonoscopy is performed on patients diagnosed with IBD, and standardized image documentation will be carried out in both WLE and TXI modes. Step biopsies are taken, and clinically validated, endoscopic, and histological scores are used.

Who May Be Eligible (Plain English)

Who May Qualify: - diagnosed by tissue sample (biopsy-confirmed) inflammatory bowel disease (ulcerative colitis or Crohn\'s disease) - Age ≥ 18 years Who Should NOT Join This Trial: - Post (procto-) colectomy - Endoscopically impassable stenosis in the left hemi-colon - ASA status \> 2 points - BBPS \< 6 points (or \< 2 points per segment) - Severe coagulation disorder - Pregnancy, lactation Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Histologically confirmed inflammatory bowel disease (ulcerative colitis or Crohn\'s disease) * Age ≥ 18 years Exclusion Criteria: * Post (procto-) colectomy * Endoscopically impassable stenosis in the left hemi-colon * ASA status \> 2 points * BBPS \< 6 points (or \< 2 points per segment) * Severe coagulation disorder * Pregnancy, lactation

Treatments Being Tested

DIAGNOSTIC_TEST

TXI mode vs. WLE mode

Experimental use of TXI mode compared to standard use of WLE to assess inflammatory activity in patients with IBD during ileocolonoscopy. Both endoscopy modes are used during the same ileocolonoscopy on the same patient.

Locations (1)

Ulm University Hospital
Ulm, Baden-Wurttemberg, Germany