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RECRUITINGOBSERVATIONAL

Prone Positioning in ARDS: Predicting Neurological Complications Via Cerebral Hemodynamics

Changes in Cerebral Blood Flow Before and After Prone Position in Patients With ARDS Predict the Occurrence of Neurological Complications

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Prone Positioning in ARDS: Predicting Neurological Complications via Cerebral Hemodynamics

Who May Be Eligible (Plain English)

Who May Qualify: - Age≥18 years - Meet the diagnostic criteria for ARDS(Acute Respiratory Distress Syndrome),with PaO₂/FiO₂\<150 mmHg,and requiring prone ventilation - Expected duration of mechanical ventilation\>48 hours - Written willing to sign a consent form obtained Who Should NOT Join This Trial: - Presence of contraindications to prone positioning(e.g.,head and neck injuries,spinal instability,severe intracranial hypertension) - Severe neurological diseases(e.g.,cerebral hemorrhage,cerebral infarction,intracranial space-occupying lesions)that may affect the monitoring of cerebral hemodynamics - Life-threatening ARDS - Patients who are unable to undergo neurological assessment - Poor image quality or absence of images Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age≥18 years * Meet the diagnostic criteria for ARDS(Acute Respiratory Distress Syndrome),with PaO₂/FiO₂\<150 mmHg,and requiring prone ventilation * Expected duration of mechanical ventilation\>48 hours * Written informed consent obtained Exclusion Criteria: * Presence of contraindications to prone positioning(e.g.,head and neck injuries,spinal instability,severe intracranial hypertension) * Severe neurological diseases(e.g.,cerebral hemorrhage,cerebral infarction,intracranial space-occupying lesions)that may affect the monitoring of cerebral hemodynamics * Life-threatening ARDS * Patients who are unable to undergo neurological assessment * Poor image quality or absence of images

Treatments Being Tested

BEHAVIORAL

Prone ventilation

Cerebral Blood Flow Monitoring Before and After Prone Ventilation in Patients with ARDS.Cerebral blood flow,intracranial pressure,and systemic hemodynamic monitoring were performed at the following time points:before prone positioning(T0),1 hour after prone ventilation(T1),12 hours after prone ventilation(T2),1 hour after returning to the supine position(T3),and 7 days after returning to the supine position(T4).

Locations (1)

Sichuan Provincial People's Hospital,
Chengdu, Sichuan, China