Quantitative Intra-operative Assessment of Parathyroid Perfusion Using Indocyanine Green (ICG) Fluorescence Imaging

Who May Qualify: - Scheduled for unilateral thyroid lobectomy plus central (VI-level) lymph-node dissection. - Intra-operative findings consistent with: - Complete identification and in-situ preservation of the ipsilateral superior parathyroid gland; - Complete identification and autotransplantation of the ipsilateral inferior parathyroid gland. - Serum 25-hydroxy-vitamin D ≥ 30 ng/mL at baseline; patients below this level may be enrolled after standardized vitamin-D and calcium supplementation with re-test confirming ≥ 30 ng/mL. - Surgery and all postoperative follow-up performed at the study center. - Able and willing to provide written willing to sign a consent form. Who Should NOT Join This Trial: - Prior surgery on the thyroid or parathyroid glands. - Severe hepatic or renal impairment, or other serious metabolic bone disease. - Pregnancy or lactation. - Known hypersensitivity to indocyanine green or iodine-containing compounds. - Inability or unwillingness to comply with postoperative visits and blood testing. Always talk to your doctor about whether this trial is right for you.