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RECRUITINGOBSERVATIONAL

Risk Factors for Microvascular Obstruction Post-Emergency PCI in AMI Patients

Triglyceride Glucol Index for Predicting the Value of No-Reflow in Patients Undergoing Emergency PCI for Acute Myocardial Infarction

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this prospective cohort study is to investigate the relationship between the TyG index and early identification of MVO in AMI patients undergoing emergency PCI and CMR imaging. The study will enroll approximately 300 AMI patients treated at Xiangya Third Hospital of Central South University from June 2024 to August 2025. The main questions it aims to answer are: * How does the TyG index correlate with the early detection of MVO? * What differences in cardiovascular adverse events during hospitalization exist between groups with varying TyG index levels? Participants will undergo emergency PCI and CMR imaging within 3-7 days post-procedure. Data collected will include demographic characteristics, clinical history, coronary angiography data, laboratory test indicators (especially metabolic markers such as blood glucose and lipids), IVUS-related plaque information, and CMR results.

Who May Be Eligible (Plain English)

Who May Qualify: - Age ≥ 18 years. - STEMI symptom onset time \< 12 hours. - STEMI symptom onset time 12-48 hours, with ongoing ischemic symptoms, hemodynamic instability, or life-threatening ventricular arrhythmias. - Very high-risk NSTEMI; undergoing emergency PCI treatment. - Voluntary signed willing to sign a consent form form. Who Should NOT Join This Trial: - Non-obstructive acute myocardial infarction. - Severe chronic kidney disease (defined as estimated glomerular filtration rate \<20 mL/min per 1.73 m²). - Pregnant women or those planning to become pregnant. - Failure of emergency PCI. - Unclear CMR images Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age ≥ 18 years. * STEMI symptom onset time \< 12 hours. * STEMI symptom onset time 12-48 hours, with ongoing ischemic symptoms, hemodynamic instability, or life-threatening ventricular arrhythmias. * Very high-risk NSTEMI; undergoing emergency PCI treatment. * Voluntary signed informed consent form. Exclusion Criteria: * Non-obstructive acute myocardial infarction. * Severe chronic kidney disease (defined as estimated glomerular filtration rate \<20 mL/min per 1.73 m²). * Pregnant women or those planning to become pregnant. * Failure of emergency PCI. * Unclear CMR images

Locations (1)

Xiangya Third Hospital of Central South University
Changsha, Hunan Province,China, China