RECRUITINGINTERVENTIONAL

Efficacy of Auricular Acupuncture Therapy in the Prevention of CIPN in Breast Cancer

Efficacy of Auricular Acupuncture Therapy Via the Seirin Pyonex Needles in the Prevention of Chemotherapy-Induced Peripheral Neuropathy(CIPN) in Breast Cancer

About This Trial

Evaluate the Efficacy of Auricular Acupuncture Therapy via the Seirin Pyonex Needles in the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer

Who May Be Eligible (Plain English)

Who May Qualify: - Patients with breast cancer diagnosed with stage I-III; - Planned to receive 4 cycles of taxane chemotherapy and have not taken neurostable drugs within three months; - 18 years old≤ age≤ 75 years old, female; - Subjects voluntarily participate in this trial and sign the willing to sign a consent form form. Who Should NOT Join This Trial: - Patients who have had acupuncture treatment in the past; - After examination by a doctor, there is a local infection at or near the acupuncture site, which is not suitable for acupuncture. - Platelets\< 50,000/μL; - Patients with CIPN≥1 grade 1 (NCI-CTCAE); - Peripheral neuropathy or other neuropathic pain caused by diabetes mellitus or other factors related to HIV infection. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * Patients with breast cancer diagnosed with stage I-III; * Planned to receive 4 cycles of taxane chemotherapy and have not taken neurostable drugs within three months; * 18 years old≤ age≤ 75 years old, female; * Subjects voluntarily participate in this trial and sign the informed consent form. Exclusion Criteria: * Patients who have had acupuncture treatment in the past; * After examination by a doctor, there is a local infection at or near the acupuncture site, which is not suitable for acupuncture. * Platelets\< 50,000/μL; * Patients with CIPN≥1 grade 1 (NCI-CTCAE); * Peripheral neuropathy or other neuropathic pain caused by diabetes mellitus or other factors related to HIV infection.

Treatments Being Tested

DEVICE

Auricular acupuncture treatment

Auricular acupuncture is an innovative intradermal acupuncture, which can directly use the meridian system of the ear skin to directly transmit the received stimulation to the lesion. Its stimulation time is long, and the amount of stimulation is strong. Studies have shown that needle pricking continuously delivers an adequate dose of acupuncture stimulation by continuously stimulating Aβ, Aδ, and/or C afferent fibers from the skin and transmitting them to the brain nucleus through the ventrolateral cord of the spinal cord. It is also believed that by stimulating the cranial nerves, especially the auricular branch of the vagus nerve, the effect of sensory afferent peripheral stimulation can be enhanced, and the analgesic effect of the auricular acupoints can be achieved.

DEVICE

Sham acupuncture group

The treatment regimen is the same as that of the auricular acupuncture treatment group, but with a sham acupuncture (Seirin Pyonex Needles).

Locations (1)

Jiangsu Provincial People's Hospital

Nanjing, Jiangsu, China