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RECRUITINGOBSERVATIONAL

Microplastic Analysis in Pediatric Inflammatory Bowel Disease

Analysis of Microplastics in Pediatric Inflammatory Bowel Disease Using Raman Spectroscopy: A Multi-Matrix Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this observational study is to measure and compare the presence of microplastics in children with inflammatory bowel disease (IBD) and children without IBD. The main questions it aims to answer are: Are microplastics detectable in different biological samples from children? Are there differences in microplastic burden between children with and without IBD? Researchers will collect biological samples including: intestinal tissue (from routine endoscopy), stool, urine, blood. Raman spectroscopy will be used to detect and characterize microplastics in each sample type. Participants will not receive any medication or intervention as part of this study. All samples will be collected during standard clinical procedures.

Who May Be Eligible (Plain English)

Who May Qualify: - Age \<18 years - Undergoing clinically indicated gastrointestinal endoscopy - For IBD group: confirmed diagnosis of Crohn's disease or ulcerative colitis - For control group: no current or past diagnosis of IBD Who Should NOT Join This Trial: - Age 18 years or older - Lack of willing to sign a consent form from legal guardian - Lack of written assent from the participant if age ≥13 years Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age \<18 years * Undergoing clinically indicated gastrointestinal endoscopy * For IBD group: confirmed diagnosis of Crohn's disease or ulcerative colitis * For control group: no current or past diagnosis of IBD Exclusion Criteria: * Age 18 years or older * Lack of informed consent from legal guardian * Lack of written assent from the participant if age ≥13 years

Treatments Being Tested

OTHER

Environmental microplastic exposure

Exposure to environmental microplastics measured by their presence in intestinal tissue, blood, urine, and stool using Raman spectroscopy. This study does not assign any exposure or treatment; it investigates the existing presence of microplastics as an environmental factor of interest.

Locations (1)

Medical University of Gdańsk, Department of Pediatrics, Gastroenterology, Allergolgy and Nutrition
Gdansk, Poland