Optimal Strategy to Correct Stent underexpAnsion in Resistant Lesions
About This Trial
Percutaneous coronary intervention (PCI) for in-stent restenosis (ISR) accounts for 5-10% of PCI. ISR may be linked to mechanical complications mainly under-expansion (UE), neointimal hyperplasia and/or neoatherosclerosis. International guidelines recommends non-compliant and very-high-pressure balloons, which lead to sub-optimal angiographic and clinical results. Recently, observational studies have suggested the feasibility and safety of intravascular lithotripsy (IVL) in UE treatment. There are no prospective randomised controlled studies comparing intravascular lithotripsy with balloons in ISR with UE.
Who May Be Eligible (Plain English)
Original Eligibility Criteria
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Treatments Being Tested
Intravascular lithotripsy
ISR with UE will be treated by intravascular lithotripsy
Balloon
ISR with UE will be treated with non compliant balloons, very high-pressure balloons, cutting balloons