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RECRUITINGOBSERVATIONAL

Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies

Utility of Optic Nerve Ultrasonography in Assessing Cerebral Inflammation and Intracranial Hypertension in Patients With Cerebral Impairment

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.

Who May Be Eligible (Plain English)

Who May Qualify: - Patients admitted into one of the specified wards of the involved hospitals - Patients aged 18-60 years - Suspected meningitis, encephalitis, stroke or cerebral tumors Who Should NOT Join This Trial: - Age under 18 years or over 60 years old - Ocular lesions preventing ocular ultrasound (palpebral infections, cornean erosions, glaucoma, trauma) - Conditions preventing lumbar puncture (coagulation disorders, epidural abscesses, local infections) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Patients admitted into one of the specified wards of the involved hospitals * Patients aged 18-60 years * Suspected meningitis, encephalitis, stroke or cerebral tumors Exclusion Criteria: * Age under 18 years or over 60 years old * Ocular lesions preventing ocular ultrasound (palpebral infections, cornean erosions, glaucoma, trauma) * Conditions preventing lumbar puncture (coagulation disorders, epidural abscesses, local infections)

Treatments Being Tested

DIAGNOSTIC_TEST

Optic Nerve Sheath Diameter

Ultrasonographic measurement of the optic nerve sheath diameter

Locations (2)

Fundeni Clinical Institute
Bucharest, Bucharest, Romania
"Dr. Victor Babeș" Clinical Hospital for Infectious and Tropical Diseases
Bucharest, Bucharest, Romania