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RECRUITINGOBSERVATIONAL

IMMUNOREA - Immunological and Inflammatory Determinants Associated With the Prognosis of Intensive Care Patients

Studies on the Immunological and Inflammatory Determinants Associated With the Prognosis of Patients Admitted to Intensive Care

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This is a prospective observational physiopathological study aimed at evaluating the immunological and inflammatory determinants associated with the prognosis of patients admitted to intensive care units (ICU). The study will establish multidimensional models predicting one-year survival and the occurrence of nosocomial infections. Patients admitted to ICU undergo routine biological sampling. In addition to these, minimal supplementary samples will be collected for immunological and inflammatory biomarker analysis at admission, day 1, day 4, day 8, ICU discharge or day 28, and at 12 months. Additional samples may be taken during clinically significant events (nosocomial infections, complications).

Who May Be Eligible (Plain English)

Who May Qualify: - Age ≥ 18 years - Admission to ICU within 24 hours Who Should NOT Join This Trial: - Moribund patient (ECOG=4) - Legal protection (guardianship/curatorship) - Uninsured patients - Pre-existing immunosuppression (active/recent cancer, hematologic disease, autoimmune conditions (where your immune system attacks your own body), organ transplant, HIV) - Pregnant or breastfeeding women - Participation in another interventional trial - Patients under AME Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age ≥ 18 years * Admission to ICU within 24 hours Exclusion Criteria: * Moribund patient (ECOG=4) * Legal protection (guardianship/curatorship) * Uninsured patients * Pre-existing immunosuppression (active/recent cancer, hematologic disease, autoimmune disease, organ transplant, HIV) * Pregnant or breastfeeding women * Participation in another interventional trial * Patients under AME

Locations (1)

AP-HP Laribosière Hospital, Anesthesia and Critical Care Departement
Paris, France