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RECRUITINGINTERVENTIONAL

Low Versus High Load Training and Parkinson's Disease

Comparison of Changes in Neuromuscular and Functional Performance Due to Resistance Training With Low-Load or High-Load in Persons With Parkinson's Disease.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This study will compare the effects of high-load resistance training to low-load resistance training, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.

Who May Be Eligible (Plain English)

Who May Qualify: - Parkinson's Disease Hoehn \& Yahr Stages 1-3 - Able to walk 50m unassisted - Able to understand and communicate in English - A Montreal Cognitive Assessment (MoCA) score above 18 Who Should NOT Join This Trial: - Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program - Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness - Unresolved injury or surgery to the upper or lower limbs that prevents weight training. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Parkinson's Disease Hoehn \& Yahr Stages 1-3 * Able to walk 50m unassisted * Able to understand and communicate in English * A Montreal Cognitive Assessment (MoCA) score above 18 Exclusion Criteria: * Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program * Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness * Unresolved injury or surgery to the upper or lower limbs that prevents weight training.

Treatments Being Tested

BEHAVIORAL

Low-Load Resistance Training

Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using three sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.

BEHAVIORAL

High-Load Resistance Training

Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using four sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.

Locations (1)

Laboratory of Neruomuscular Research and Active Aging
Coral Gables, Florida, United States