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RECRUITINGINTERVENTIONAL

Tai Chi and Square-Stepping Exercises in Women With Multiple Sclerosis

The Effects of Tai Chi and Square Stepping Exercises on Joint Position Sense and Clinical Outcomes in Women With Multiple Sclerosis

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Tai Chi is an exercise approach consisting of slow and controlled movements, whereas square stepping exercises are an exercise method in which specific step patterns are followed. The aim of this study is to comparatively examine the effects of Tai Chi and Square Stepping Exercises on knee joint position sense, lower extremity muscle strength, and fatigue levels in women with multiple sclerosis.

Who May Be Eligible (Plain English)

Who May Qualify: - Willing to participate and provide willing to sign a consent form. - Diagnosed with multiple sclerosis (MS) according to the McDonald diagnostic criteria. - Relapsing-remitting MS (RRMS) phenotype. - EDSS score \< 3.5. - Female, 20-45 years of age. - No MS relapse within the past 1 month. - No lower-extremity spasticity according to the Modified Ashworth Scale (MAS). Who Should NOT Join This Trial: - Any neurological disease other than MS. - Experiencing an MS relapse during the study period. - History of orthopedic surgery that may affect balance. - Cognitive or psychiatric impairment that may interfere with study participation. - Cardiovascular or pulmonary history that may prevent participation. - Use of medications that may affect clinical assessment (e.g., antipsychotic use; continuous corticosteroid or immunosuppressive use within the past 1 month). - Participation in any other exercise program Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Willing to participate and provide informed consent. * Diagnosed with multiple sclerosis (MS) according to the McDonald diagnostic criteria. * Relapsing-remitting MS (RRMS) phenotype. * EDSS score \< 3.5. * Female, 20-45 years of age. * No MS relapse within the past 1 month. * No lower-extremity spasticity according to the Modified Ashworth Scale (MAS). Exclusion Criteria: * Any neurological disease other than MS. * Experiencing an MS relapse during the study period. * History of orthopedic surgery that may affect balance. * Cognitive or psychiatric impairment that may interfere with study participation. * Cardiovascular or pulmonary history that may prevent participation. * Use of medications that may affect clinical assessment (e.g., antipsychotic use; continuous corticosteroid or immunosuppressive use within the past 1 month). * Participation in any other exercise program

Treatments Being Tested

BEHAVIORAL

Tai Chi

Tai Chi will be delivered for 8 weeks, 2 days per week, 1 session per day (total 16 sessions). Each session will last approximately 45-60 minutes and will include warm-up stretching, main Tai Chi practice, and cool-down stretching plus controlled breathing techniques.

BEHAVIORAL

Square Stepping Exercise (SSE)

SSE will be delivered for 8 weeks, 2 days per week, 1 session per day (total 16 sessions). Each session will be completed in approximately 45-60 minutes, including warm-up and cool-down periods.

BEHAVIORAL

Home-based Frenkel Coordination Exercises

Frenkel Coordination Exercises will be delivered as a home program for 8 weeks, 2 days per week, 1 session per day (total 16 sessions). Each session will last 15-30 minutes, excluding rest periods.

Locations (1)

Department of Neurology, Pamukkale University Hospital
Denizli, Turkey (Türkiye)