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RECRUITINGOBSERVATIONAL

Management of Pancreatic Cystic Lesions Using Artificial Intelligence Based on EUS and Multimodal Data

A Multimodal Artificial Intelligence Model for Subtyping Diagnosis and Clinical Management of Pancreatic Cystic Lesions Based on Endoscopic Ultrasound and Clinical Information

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The primary objective is to construct a multimodal AI model (Cyst-AI) based on EUS images and clinical data such as imaging features(CT or MRI) and laboratory tests to assist endoscopists in the diagnosis of pancreatic cystic lesions(PCLs), mainly differentiating mucinous from non-mucinous lesions. The secondary objective is to evaluate the model's effectiveness in risk stratification and clinical management for patients with PCLs.

Who May Be Eligible (Plain English)

Who May Qualify: - Patients whose EUS results indicates pancreatic cystic or cystoid lesions; - Mucinous lesions: including mucinous cystic neoplasm (MCN), intraductal papillary mucinous neoplasm (IPMN); - Non-mucinous lesions: including pancreatic pseudocyst, serous cystic neoplasm (SCN), cystic neuroendocrine tumor (cNET). Who Should NOT Join This Trial: - Patients whose age is less than 18 years old; - Patients who have undergone pancreatic surgery before the EUS examination; - Patients who have received chemotherapy and radiotherapy for pancreatic tumors before the EUS examination; - Pathological results indicate that pancreatic lesions are metastatic lesions from other sites; - Patients whose EUS images or reports are missing; - EUS image quality does not meet the requirements for review, such as blurry imaging or containing artifacts, biopsy needles, measuring scales, or other additional annotations that are not part of the original EUS image; - Patients whose final diagnosis is unclear. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion criteria: * Patients whose EUS results indicates pancreatic cystic or cystoid lesions; * Mucinous lesions: including mucinous cystic neoplasm (MCN), intraductal papillary mucinous neoplasm (IPMN); * Non-mucinous lesions: including pancreatic pseudocyst, serous cystic neoplasm (SCN), cystic neuroendocrine tumor (cNET). Exclusion criteria: * Patients whose age is less than 18 years old; * Patients who have undergone pancreatic surgery before the EUS examination; * Patients who have received chemotherapy and radiotherapy for pancreatic tumors before the EUS examination; * Pathological results indicate that pancreatic lesions are metastatic lesions from other sites; * Patients whose EUS images or reports are missing; * EUS image quality does not meet the requirements for review, such as blurry imaging or containing artifacts, biopsy needles, measuring scales, or other additional annotations that are not part of the original EUS image; * Patients whose final diagnosis is unclear.

Treatments Being Tested

DIAGNOSTIC_TEST

Cyst-AI model

The multi-center collected data will be divided into a training set, a validation set, and a test set for developing and testing the cyst-AI model.

Locations (2)

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China