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Beta-Thalassemia Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

5 recruiting trials for Beta-Thalassemia. Eligibility criteria explained in plain English.

TrialFinderData lists 5 Beta-Thalassemia clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 1 / Phase 2 is the largest group at 25% (1 studies); the largest phase groups are Phase 1 / Phase 2: 1, Phase 2: 1, Phase 1: 1, Phase 3: 1.

Research is led by xCures (1), National Heart, Lung, and Blood Institute (NHLBI) (1), Mitchell Cairo (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Total Body Irradiation (radiation, 1 trial), followed by Alemtuzumab, Abatacept.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
5
Total Trials
5
Recruiting Now
1
Phase 3 Trials
5
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT06539169

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

FLOWER is a completely virtual, nationwide, real-world observational study to collect, annotate, standardize, and report clinical data for rare diseases. Patients participate in...

Sponsor: xCuresEnrolling: 10001 location
RECRUITINGPhase 1 / Phase 2NCT07599176

Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors

This is a non-ablative (partial) stem cell transplant for patients with severe sickle cell disease or beta-thalassemia requiring red cell transfusions. The intensity of the...

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)Enrolling: 901 location
RECRUITINGPhase 2NCT04099966

AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion

Children, adolescents, and young adults with malignant and non-malignant conditionsundergoing an allogeneic stem cell transplantation (AlloSCT) will have the stem cells selected...

Sponsor: Mitchell CairoEnrolling: 201 location
RECRUITINGPhase 1NCT06647979

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

A promising approach for the treatment of genetic diseases is called gene therapy. Gene therapy is a relatively new field of medicine that uses genetic material (mostly DNA) from...

Sponsor: Daniel BauerEnrolling: 101 location
RECRUITINGPhase 3NCT05477563

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia...

This is a single-dose, open-label study in participants with transfusion-dependent β-thalassemia (TDT) or severe sickle cell disease (SCD). The study will evaluate the safety and...

Sponsor: Vertex Pharmaceuticals IncorporatedEnrolling: 266 locations

Frequently Asked Questions

There are currently 5 clinical trials for Beta-Thalassemia, with 5 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Beta-Thalassemia, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Beta-Thalassemia, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.