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Vertex Pharmaceuticals Incorporated

4 clinical trials · 4 recruiting · INDUSTRY

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Vertex Pharmaceuticals Incorporated

RECRUITINGPhase 1NCT07437105

Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of single and multiple ascending doses of VX-272.

Sponsor: Vertex Pharmaceuticals IncorporatedEnrolling: 1281 location
Cystic Fibrosis
RECRUITINGPhase 1 / Phase 2NCT05668741

A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)

The purpose of this study is to evaluate the safety, and tolerability and efficacy of VX-522 in participants 18 years of age and older with cystic fibrosis and a cystic fibrosis...

Sponsor: Vertex Pharmaceuticals IncorporatedEnrolling: 3920 locations
Cystic Fibrosis
RECRUITINGPhase 1NCT06154447

Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis

The purpose of the study is to evaluate safety, tolerability, and pharmacokinetics of VX-828 and VX-828 in triple combination (TC) with Tezacaftor (TEZ)/ VX-118 or TEZ/...

Sponsor: Vertex Pharmaceuticals IncorporatedEnrolling: 25511 locations
Cystic Fibrosis
RECRUITINGPhase 1NCT07283770

Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy Participants

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of single and multiple ascending doses of VX-581.

Sponsor: Vertex Pharmaceuticals IncorporatedEnrolling: 1281 location
Cystic Fibrosis