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Down Syndrome Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

7 recruiting trials for Down Syndrome. Eligibility criteria explained in plain English.

TrialFinderData lists 7 Down Syndrome clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Every phased trial in this set is Phase 4 (2 of the listed studies); the remaining records are observational or have no phase recorded on ClinicalTrials.gov.

Research is led by Duke University (2), University of North Carolina, Chapel Hill (1), Children's Hospital Medical Center, Cincinnati (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is PACE Program (behavioral, 1 trial), followed by Retinal and Choroidal Imaging, Quillivant XR.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
7
Total Trials
7
Recruiting Now
0
Phase 3 Trials
6
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT06740162

Physical Activity and Community EmPOWERment Project

Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet...

Sponsor: University of North Carolina, Chapel HillEnrolling: 3762 locations
RECRUITINGNCT03233646

Retinal Imaging in Neurodegenerative Disease

This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus...

Sponsor: Duke UniversityEnrolling: 20001 location
RECRUITINGPhase 4NCT04219280

Evaluating Treatment of ADHD in Children with Down Syndrome

Children with Down syndrome (DS) have a 3-5 time greater prevalence of Attention Deficit Hyperactivity Disorder (ADHD) than typically developing (TD) children. Despite this higher...

Sponsor: Children's Hospital Medical Center, CincinnatiEnrolling: 1004 locations
RECRUITINGNCT04278404

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of...

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults...

Sponsor: Duke UniversityEnrolling: 500020 locations
RECRUITINGPhase 4NCT07280468

Endotype DIrected Treatment for OSA in Down Syndrome

Down syndrome is the most common genetic cause of intellectual disability. People with Down syndrome often have obstructive sleep apnea (OSA), a condition where people have...

Sponsor: University of ArizonaEnrolling: 2005 locations
RECRUITINGNCT05527652

Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

The researchers are investigating if the Self-Supporting Nasopharyngeal Airway (ssNPA) device can be used in the treatment of obstructive sleep apnea in children with Hypotonic...

Sponsor: University of MichiganEnrolling: 401 location
RECRUITINGNCT06061562

Down Syndrome, Physical Activity and Sleep Apnea

To realize a sleep phenotyping in a population with Down syndrome, its determinants, and the consequences of these disorders, with a specific focus on sleep apnea syndrome.

Sponsor: University Hospital, GrenobleEnrolling: 501 location

Frequently Asked Questions

There are currently 7 clinical trials for Down Syndrome, with 7 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Down Syndrome, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 0 Phase 3 trials for Down Syndrome, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.