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University of North Carolina, Chapel Hill

17 clinical trials · 17 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by University of North Carolina, Chapel Hill

RECRUITINGNCT05320822

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

The strategic objective of this research line is to examine improving short- and long-term outcomes for soldiers following mild traumatic brain injury (mTBI). The technical...

Sponsor: University of North Carolina, Chapel HillEnrolling: 1302 locations
Concussion, Brain
RECRUITINGPhase 2NCT06059664

The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study

EFFEKTOR is a vanguard, multicenter, phase 2 randomized, double blinded, placebo controlled clinical trial to determine the feasibility, tolerability, safety, and efficacy of...

Sponsor: University of North Carolina, Chapel HillEnrolling: 1501 location
Kidney Transplant; Complications
RECRUITINGNCT05741125

Improving Appetite Self-Regulation in African American Adults With Type 2 Diabetes

The purpose of this 6-month randomized clinical trial is to examine the feasibility of recruitment, attendance, retention, program adherence, and satisfaction of a digital...

Sponsor: University of North Carolina, Chapel HillEnrolling: 602 locations
Type 2 DiabetesBinge Eating
RECRUITINGNCT05693896

Treating Binge Eating and Obesity Digitally in Black Women

More than 30% of Black women with obesity binge eat. Binge eating may increase the risk for the development of metabolic syndrome and binge-eating-disorder (BED), which is...

Sponsor: University of North Carolina, Chapel HillEnrolling: 601 location
Binge EatingBinge-Eating DisorderWeight Gain Prevention+1
RECRUITINGNCT06060860

Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults

Autistic adults are at a greater risk for mental health problems compared to the general population, with 50% meeting criteria for a co-occurring psychiatric condition. Depression...

Sponsor: University of North Carolina, Chapel HillEnrolling: 3002 locations
Autism Spectrum DisorderDepressionAnxiety
RECRUITINGNCT07237516

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

The goal of this observational study is to learn about how effective Zymfentra (IFX=dyyb) is when treating patients with Crohn's disease (CD) and ulcerative colitis (UC) Does...

Sponsor: University of North Carolina, Chapel HillEnrolling: 2005 locations
Ulcerative Colitis (UC)Crohn's Disease (CD)Indeterminate Colitis+1
RECRUITINGNCT07337902

Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)

The purpose of this pilot study is to prepare for a larger study that will compare the effectiveness and safety of two common pain medications, ibuprofen and acetaminophen, to...

Sponsor: University of North Carolina, Chapel HillEnrolling: 241 location
Crohn's Disease (CD)Dysmenorrhea Primary
RECRUITINGNCT06696014

Mirikizumab Real World Protocol

The goal of this observational study is to learn about how effective mirikizumab (Omvoh) is when treating patients with ulcerative colitis (UC) Does mirikizumab (Omvoh) lead to a...

Sponsor: University of North Carolina, Chapel HillEnrolling: 1009 locations
Ulcerative Colitis
RECRUITINGNCT06405373

Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART

This study is designed to compare two behavioral approaches to reduce diabetes distress ("the expected burdens, concerns, fears, and threats that arise from the challenges of...

Sponsor: University of North Carolina, Chapel HillEnrolling: 2001 location
Diabetes type1Diabetes Mellitus, Type 1Diabetes, Autoimmune+2
RECRUITINGNCT05026723

Food as Medicine for HIV and Diabetes

This is a single-site, open-label, Phase II, community-based randomized controlled explanatory trial to test the efficacy of a medically tailored meal + intensive lifestyle...

Sponsor: University of North Carolina, Chapel HillEnrolling: 2001 location
Diabetes Mellitus, Type 2HIV InfectionsPreDiabetes
RECRUITINGNCT07126587

Healthy Living Anson Study

The goal of this randomized delayed control intervention research study is to see if participants who receive education and healthy prepared meals improve the quality of their...

Sponsor: University of North Carolina, Chapel HillEnrolling: 1201 location
Obesity (Disorder)Diabetes Type 2Heart Disease+3
RECRUITINGNCT06057714

Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis

The purpose of this study is to look at lung ventilation in people with cystic fibrosis over time (1 year) using magnetic resonance imaging (MRI) with an inhaled contrast gas, and...

Sponsor: University of North Carolina, Chapel HillEnrolling: 301 location
Cystic FibrosisVentilatory Defect
RECRUITINGNCT06066723

19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease

This study capitalizes on the emerging technology of 19F MRI, using conventional 'thermally' polarized perfluorinated gas (perfluoropropane, or PFP) mixed with oxygen and studied...

Sponsor: University of North Carolina, Chapel HillEnrolling: 151 location
Cystic Fibrosis in Children
RECRUITINGPhase 4NCT06242795

Hypertonic Saline in NCFB

The purpose of this single arm clinical trial is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on clearance of mucus from the lungs in people with...

Sponsor: University of North Carolina, Chapel HillEnrolling: 201 location
BronchiectasisNon-cystic Fibrosis Bronchiectasis
RECRUITINGNCT00807482

Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease

The overall short-term goals of this project include the following: 1) identify the genes that are key to the function of respiratory cilia to protect the normal lung; and 2) the...

Sponsor: University of North Carolina, Chapel HillEnrolling: 18001 location
Kartagener Syndrome
RECRUITINGNCT06931431

UNCPM 22322 - Adaption of the Transition of Care Model for Post-Discharge HIV-NCD Care in Lilongwe, Malawi - MLATHO

This is an implementation research study that will adapt and pilot test the Transitional Of Care Model (TCM), originally conceived and developed in the USA, for targeted use as a...

Sponsor: University of North Carolina, Chapel HillEnrolling: 751 location
HIVNoncommunicable Diseases
RECRUITINGNCT06173544

HIV Engagement and Adolescent Depression Support (HEADS-UP)

This pilot study will individually randomize 105 adolescents living with HIV 1:1:1 to standard of care, adapted intervention, or enhanced intervention. The intervention is called...

Sponsor: University of North Carolina, Chapel HillEnrolling: 1055 locations
DepressionAnxietyAdolescent Behavior+2