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TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Dry Eye Clinical Trials

21 recruiting trials for Dry Eye. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
21
Total Trials
21
Recruiting Now
1
Phase 3 Trials
10
Sponsors

Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 4NCT06017362

Clinical Trial to Determine the Efficacy and Safety of Insulin Eye Drops in Dry Eye in Patients with Topical Hypotensors

The goal of this clinical trial is to evaluate the preliminary efficacy of the use of insulin eye drops in the control of dry eye disease in patients with topical hypotensors,...

Sponsor: Barbara Burgos BlascoEnrolling: 1001 location
RECRUITINGPhase 1 / Phase 2NCT07298811

Preliminary Clinical Study of the Effectiveness and Safety of Ocular Surface Microbiota Transplantation in the...

Evaluate the efficacy and safety of ocular surface microbiota transplantation as an adjunctive therapy for dry eye, and explore its impact on the structure of the ocular surface...

Sponsor: Second Affiliated Hospital of Nanchang UniversityEnrolling: 401 location
RECRUITINGPhase 4NCT07191847

Assessment of CataClear, Tear Film Stability, Tear Volume, and Dry Eye Symptoms Using Stem Cells Fortified Eye Drops

Dry Eye Disease (DED) is a multifactorial condition that affects the ocular surface, leading to discomfort, tear film instability, and potential visual disturbances. Its global...

Sponsor: Ace Cells Lab LimitedEnrolling: 3001 location
RECRUITINGPhase 3NCT06392438

Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens Users

In this study, two treatments typically used for dry eye disease will be tried for contact lens users to see if their symptoms when they use their contact lenses get better....

Sponsor: Université de SherbrookeEnrolling: 441 location
RECRUITINGNCT06513000

Dryness Difference Between Before and After Phacoemulsification

The aim of this study is to compare tear film and tear film secretion before and after phacoemulsificaton cataract surgery

Sponsor: Sohag UniversityEnrolling: 1001 location
RECRUITINGNCT06841471

Role of Corneal Nerves in Dry Eye Disease

This study aims to determine whether corneal nerve function and morphology are affected by tear film instability and ocular surface homeostasis loss. Additionally, it seeks to...

Sponsor: Daniela NoschEnrolling: 1401 location
RECRUITINGNCT05552820

Electroacupuncture for Mild-to-moderate Dry Eye

To determine if electroacupuncture acts as an dry eye treatment rather than a placebo, and identify if benefits are linked to corneal subbasal nerve changes and...

Sponsor: Shanghai Institute of Acupuncture, Moxibustion and MeridianEnrolling: 1681 location
RECRUITINGNCT07089511

Cord Blood Platelet Poor Plasma Eye Drops

Dry eye disease (DED) is a prevalent ocular condition characterized by the disruption of the ocular surface's homeostasis. It affects a significant portion of the population,...

Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoEnrolling: 1001 location
RECRUITINGEarly Phase 1NCT07245017

JN002 for the Treatment of Dry Eye Disease

This is a first-in-human, single-center, randomized, double-blind, placebo-controlled clinical trial designed to:·Evaluate the efficacy of JN002 Ophthalmic Solution in treating...

Sponsor: Eye & ENT Hospital of Fudan UniversityEnrolling: 301 location
RECRUITINGPhase 1 / Phase 2NCT06544447

Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction

Objective: To evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) for the patients with dry eye disease with meibomian gland dysfunction. Methods: We...

Sponsor: Beijing Tongren HospitalEnrolling: 1351 location
RECRUITINGPhase 4NCT06964269

Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune...

Single-site, open label pilot study of 20 autoimmune patients diagnosed with dry eye demonstrating via the proparacaine challenge some peripheral corneal pain component. At least...

Sponsor: Toyos ClinicEnrolling: 201 location
RECRUITINGPhase 4NCT07266948

Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work

This 1-month, 3-visit study will be conducted at the Southern College of Optometry (Memphis, TN), Kannarr Eye Care, LLC (Pittsburg, KS) and Complete Eye Care of Medina...

Sponsor: Southern College of OptometryEnrolling: 403 locations
RECRUITINGPhase 4NCT06975891

Performance of Systane PRO Versus Refresh Optive Mega-3

Single site, prospective, double-masked, randomized-controlled, cross-over study of the subjective and objective performance of 2 different eyedrops. Subjects will be assessed at...

Sponsor: Scripps Poway Eyecare and OptometryEnrolling: 351 location
RECRUITINGPhase 2NCT07179055

An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

The purpose of this study is to determine the safety and efficacy of VSJ-110 compared to placebo in the treatment of dry eye.

Sponsor: Vanda PharmaceuticalsEnrolling: 1605 locations
RECRUITINGNCT06893913

Effect of Addition of Pyramidal Exercise to Intermittent Fasting on Dryness of Eye in Pre-diabetic Psoriasis Patients

insulin resistant psoriatic obese patients may complain problems of dryness of eye. Intermittent fasting may improve dryness of eye, obesity, insulin resistance, and psoriasis....

Sponsor: Cairo UniversityEnrolling: 401 location
RECRUITINGNCT07173530

Low Level Light Therapy & Skin Pigmentation

The goal of this clinical trial is to determine if there is a difference in eyelid temperature after low-level light therapy (LLLT) in individuals with different amounts of skin...

Sponsor: University of HoustonEnrolling: 401 location
RECRUITINGPhase 4NCT07510620

Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses

This research study is to see if using Lacrifill is safe, easy to use, and helpful for people who wear contact lenses but can't wear them comfortably for long. Specifically, the...

Sponsor: Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care SpecialistsEnrolling: 301 location
RECRUITINGNCT04129021

High Resolution, High-speed Multimodal Ophthalmic Imaging

Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging. However, current clinical...

Sponsor: Centre Hospitalier National d'Ophtalmologie des Quinze-VingtsEnrolling: 12001 location
RECRUITINGNCT07329712

Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy

The purpose of this research study is to understand the mechanism of action of low level light therapy and also potentially yield markers associated with good treatment response....

Sponsor: Singapore National Eye CentreEnrolling: 301 location
RECRUITINGPhase 2NCT06543303

Evaluation of BTV100 in Subjects With Dry Eye Disease

This study will be a randomized, vehicle-controlled, double-masked, multiple-dose, parallel-group study to evaluate the efficacy, safety and tolerability of repeat dosing of...

Sponsor: BioTheraVision, Inc.Enrolling: 1206 locations
RECRUITINGNCT06565091

Clinical Investigation for a Multifunction Ophthalmic Measurement Device

The purpose of this clinical investigation is to evaluate the clinical utility of a multifunctional measuring device for Ophtalmology. The results of this clinical investigation...

Sponsor: Essilor InternationalEnrolling: 3781 location

Frequently Asked Questions

There are currently 21 clinical trials for Dry Eye, with 21 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Dry Eye, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Dry Eye, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice — always talk to your doctor about clinical trial participation.