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Gastroesophageal Junction Adenocarcinoma Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

13 recruiting trials for Gastroesophageal Junction Adenocarcinoma. Eligibility criteria explained in plain English.

TrialFinderData lists 13 Gastroesophageal Junction Adenocarcinoma clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 2 is the largest group at 40% (4 studies); the largest phase groups are Phase 2: 4, Phase 1: 2, Phase 3: 2, Phase 2 / Phase 3: 1.

Research is led by Mayo Clinic (2), University of Chicago (1), Cofactor Genomics, Inc. (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Oxaliplatin (drug, 5 trials), followed by Nivolumab, Leucovorin.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
13
Total Trials
13
Recruiting Now
2
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 1NCT04361708

Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies

The purpose of the proposed study is to establish the safety of combining irinotecan chemotherapy with 5-FU, leucovorin/folinic acid, oxaliplatin, and docetaxel (abbreviated as...

Sponsor: University of ChicagoEnrolling: 541 location
RECRUITINGPhase 2NCT06265285

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access...

This phase II trial compares the impact of subcutaneous (SC) nivolumab given in an in-home setting to an in-clinic setting on cancer care and quality of life. Currently, most...

Sponsor: Mayo ClinicEnrolling: 501 location
RECRUITINGNCT04510129

A Multicenter Cancer Biospecimen Collection Study

This study will collect de-identified tumor samples, with correlated clinical/demographic data and tissue histology, from patients selected or scheduled for pre-treatment tumor...

Sponsor: Cofactor Genomics, Inc.Enrolling: 16501 location
RECRUITINGPhase 2NCT03175224

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

To assess: * efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET...

Sponsor: Apollomics Inc.Enrolling: 49720 locations
RECRUITINGNCT05334069

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and...

Sponsor: Alliance for Clinical Trials in OncologyEnrolling: 200020 locations
RECRUITINGPhase 1NCT05802056

Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis

This phase Ib trial test effects of aldesleukin in combination with nivolumab and standard chemotherapy in treating patients with gastric cancer that has spread to the tissue...

Sponsor: Mayo ClinicEnrolling: 151 location
RECRUITINGPhase 2NCT06560528

Disitamab Vedotin Combined With Tislelizumab and Capecitabine in the Perioperative Treatment of Locally Advanced...

The efficacy and safety of combination with Disitamab Vedotin and with Tislelizumab and Capecitabine for perioperative treatment of locally advanced gastric cancer with HER2...

Sponsor: Tianjin Medical University Cancer Institute and HospitalEnrolling: 402 locations
RECRUITINGPhase 2 / Phase 3NCT07001748

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With...

This study is being done to answer the following questions: Can we lower the chance of your gastric cancer from growing or spreading by administering paclitaxel chemotherapy...

Sponsor: ECOG-ACRIN Cancer Research GroupEnrolling: 14820 locations
RECRUITINGPhase 3NCT04447352

HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT)

This is a multicenter, randomized, controlled, open-label study evaluating efficacy and safety of perioperative FLOT chemotherapy plus intraoperative HIPEC versus FLOT...

Sponsor: Krankenhaus NordwestEnrolling: 20015 locations
RECRUITINGPhase 1 / Phase 2NCT06324357

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to...

This study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery. People can take part in this study if...

Sponsor: Boehringer IngelheimEnrolling: 76820 locations
RECRUITINGPhase 3NCT07431281

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or...

The purpose of this study is to evaluate the efficacy and safety of sonesitatug vedotin in combination with capecitabine with or without rilvegostomig in first-line (1L)...

Sponsor: AstraZenecaEnrolling: 213020 locations
RECRUITINGPhase 2NCT05476796

Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced,...

Oxaliplatin ± nivolumab in combination with trifluridine/tipiracil or 5-fluorouracile (5-FU) in frail patients with advanced, recurrent or metastatic gastric, oesophageal or...

Sponsor: UNICANCEREnrolling: 11820 locations
RECRUITINGNCT04290806

Registry Platform Gastric/Esophageal Cancer (SAPHIR)

The registry aims to collect and analyse information on the antineoplastic treatment of patients with metastatic esophageal, gastric or gastroesophageal junction cancer, treated...

Sponsor: iOMEDICO AGEnrolling: 19001 location

Frequently Asked Questions

There are currently 13 clinical trials for Gastroesophageal Junction Adenocarcinoma, with 13 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Gastroesophageal Junction Adenocarcinoma, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 2 Phase 3 trials for Gastroesophageal Junction Adenocarcinoma, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.