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Updated June 2026 · ClinicalTrials.gov

Pfizer

Reviewed by TrialFinderData Editorial Team · Updated

25 clinical trials · 25 recruiting · INDUSTRY

Pfizer has 25 clinical trials registered on ClinicalTrials.gov, with 25 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Pfizer\'s Trial Portfolio

Pfizer is an industry sponsor — typically a pharmaceutical, biotechnology, or medical device company. Industry sponsors fund and run the largest share of registered trials in the United States and are subject to FDA registration requirements under the FDA Amendments Act (FDAAA 801) for most drug and device studies.

25 of Pfizer's 25 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Pfizer's research footprint spans Acute Treatment of Migraine (3 trials), COVID-19 (3), and Hemophilia A (3) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Pfizer's portfolio is weighted toward later-stage research — Phase 3 accounts for 40% of registered trials. Later-stage trials are the ones most likely to lead directly to FDA approval decisions, and they typically enroll the largest patient cohorts.

Trials by Pfizer

RECRUITINGPhase 3NCT07062965

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With...

The purpose of this study is to learn about the safety and effects of the study medicine PF-07248144 when given along with fulvestrant for the possible treatment of HR-positive,...

Sponsor: PfizerEnrolling: 40020 locations
Breast Cancer
RECRUITINGPhase 1NCT07318805

A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

The purpose of this study is to learn about the safety and effects of the study medicine when given alone or together with other anti-cancer therapies. Anti-cancer therapy is a...

Sponsor: PfizerEnrolling: 2609 locations
Advanced Breast CancerMetastatic Breast Cancer (HR+/ HER2-)Colorectal Cancer+2
RECRUITINGPhase 1NCT05355701

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07799933) administered as a single agent and in combination with other...

Sponsor: PfizerEnrolling: 26720 locations
MelanomaNon-Small-Cell Lung CancerThyroid Cancer+2
RECRUITINGPhase 1 / Phase 2NCT07227012

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination...

The purpose of this study is to learn about the effects of study medicine (PF-08634404) when given alone or with another antibody (ipilimumab) for the treatment of a type of liver...

Sponsor: PfizerEnrolling: 13820 locations
Carcinoma, HepatocellularHepatocellular CancerHepatocellular Carcinoma+4
RECRUITINGPhase 1NCT05538130

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced...

The purpose of this clinical trial is to learn the safety and effects of the study medicine (PF-07799544) alone or in combination as a potential cancer treatment for adults with...

Sponsor: PfizerEnrolling: 12420 locations
MelanomaGliomaThyroid Cancer+10
RECRUITINGPhase 3NCT06152575

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That...

The purpose of this study is to learn about the study medicine called elranatamab.This study aims to compare elranatamab to other medicines for the treatment of MM (a type of...

Sponsor: PfizerEnrolling: 49220 locations
Multiple Myeloma
RECRUITINGPhase 3NCT06641466

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual...

The purpose of this study is to evaluate the efficacy and safety of rimegepant when administered during the peri-menstrual period (PMP) for intermittent prevention of migraine in...

Sponsor: PfizerEnrolling: 72320 locations
Menstrual Migraine
RECRUITINGPhase 3NCT04743141

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of migraine in children and adolescents (≥ 6 to \< 18 years of age).

Sponsor: PfizerEnrolling: 60020 locations
Acute Treatment of Migraine
RECRUITINGPhase 4NCT07609914

A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine

Acute treatments for migraine may not provide sufficient pain relief after an initial dose, and a second dose of a given medication may be needed to fully abort an attack....

Sponsor: PfizerEnrolling: 4003 locations
Acute Treatment of Migraine
RECRUITINGPhase 1NCT06995729

A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine

The purpose of the study is to learn about safety and how the body processes the study medicine called Zavegepant (PF-07930207) in children with a history of migraine. This study...

Sponsor: PfizerEnrolling: 1613 locations
Acute Treatment of Migraine
RECRUITINGPhase 2NCT07073820

A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have...

The purpose of this study is to learn about the long-term safety, tolerability and effects of the study medicine (PF-07868489) for the possible treatment of PAH. PAH is a...

Sponsor: PfizerEnrolling: 3620 locations
Pulmonary Hypertension
RECRUITINGPhase 2NCT05287126

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in...

Sponsor: PfizerEnrolling: 3620 locations
Ulcerative Colitis
RECRUITINGNCT06294925

A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis

The purpose of this real world non-interventional study is to learn about the effects of etrasimod as treatment for patients with moderate to severe ulcerative colitis. Patients...

Sponsor: PfizerEnrolling: 36020 locations
Colitis, Ulcerative
RECRUITINGPhase 2NCT06977581

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) for the potential treatment of moderate-to-severe asthma....

Sponsor: PfizerEnrolling: 25220 locations
Asthma
RECRUITINGPhase 1NCT07552779

A Study of How Ibuzatrelvir is Taken up Into the Blood of Healthy Adults After Taking Different Tablets of Ibuzatrelvir

Healthy adults will be enrolled into this open-label, Phase 1 research study. Participants will spend about 9 nights and 10 days in the clinical research unit (CRU) and the total...

Sponsor: PfizerEnrolling: 181 location
Coronavirus Disease 2019Coronavirus Disease 2019 (COVID-19)COVID-19 (Coronavirus Disease 2019)+8
RECRUITINGNCT05733104

A Study to Learn About the Study Medicine Zavicefta After it is Released Into the Markets in Korea

The purpose of this study is to learn about the safety and effectiveness of Zavicefta once released into the markets in Korea. This study is to learn about Zavicefta in patients...

Sponsor: PfizerEnrolling: 6001 location
Complicated Intra-abdominal InfectionComplicated Urinary Tract InfectionHospital-acquired Pneumonia
RECRUITINGPhase 3NCT05261139

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18...

The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and eliminated from your body after...

Sponsor: PfizerEnrolling: 16020 locations
COVID-19
RECRUITINGNCT05890612

A Study on Paxlovid Once in the Market, to Observe Its Safety and Effectiveness in Patients Who Have a High Chance of...

The purpose of this study is to look at the safety and effectiveness of PAXLOVID in the real world and not in clinical studies. The study observes patients who have a high chance...

Sponsor: PfizerEnrolling: 30001 location
COVID-19
RECRUITINGPhase 3NCT06866405

A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a...

This study aims to check how safe and well-tolerated a second dose of RSVpreF is when given during later pregnancies, and to see how long the immunity lasts from a single dose...

Sponsor: PfizerEnrolling: 55020 locations
RSV Infection
RECRUITINGPhase 3NCT07543380

A Study to Learn Safety and Immune Response to Study Vaccine -RSVpreF in Adults at High Risk of Severe RSV Disease.

The purpose of the study is to learn about the immune response after a RSVpreF vaccination. This study is being conducted in Japan. RSV is a common virus that can cause infections...

Sponsor: PfizerEnrolling: 1305 locations
Respiratory Syncytial Virus (RSV)
RECRUITINGPhase 2NCT07431853

A Study to Learn About mRNA Vaccines Against Influenza in Adults

The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune...

Sponsor: PfizerEnrolling: 77015 locations
Healthy Adults
RECRUITINGPhase 3NCT05611801

A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called marstacimab) for the potential treatment of hemophilia in pediatric...

Sponsor: PfizerEnrolling: 10020 locations
Hemophilia AHemophilia B
RECRUITINGPhase 1NCT06703606

A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.

The purpose of the study is to learn about safety, how the body processes marstacimab and how it works in patients with severe hemophilia A without inhibitors. Hemophilia A is...

Sponsor: PfizerEnrolling: 157 locations
Severe Hemophilia A
RECRUITINGPhase 3NCT05568719

Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B...

A study to learn about the long-term safety and efficacy of giroctocogene fitelparvovec or fidanacogene elaparvovec in patients with hemophilia A or hemophilia B respectively, who...

Sponsor: PfizerEnrolling: 17320 locations
Hemophilia AHemophilia B
RECRUITINGPhase 3NCT05145127

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

Study B7841007 is an open-label extension study to assess the long-term safety, tolerability, and efficacy of prophylaxis treatment with marstacimab in participants who did not...

Sponsor: PfizerEnrolling: 24520 locations
Hemophilia AHemophilia B

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Pfizer have on ClinicalTrials.gov?

Pfizer has 25 clinical trials registered on the federal ClinicalTrials.gov registry, of which 25 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Pfizer study?

Pfizer's registered trials cover 20 conditions on ClinicalTrials.gov, led by Acute Treatment of Migraine (3 trials), COVID-19 (3 trials), Hemophilia A (3 trials), Hemophilia B (3 trials), Melanoma (2 trials). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Pfizer clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 25 trials tracked for Pfizer.