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Pfizer

24 clinical trials · 24 recruiting · INDUSTRY

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Pfizer

RECRUITINGPhase 1NCT05538130

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced...

The purpose of this clinical trial is to learn the safety and effects of the study medicine (PF-07799544) alone or in combination as a potential cancer treatment for adults with...

Sponsor: PfizerEnrolling: 12420 locations
MelanomaGliomaThyroid Cancer+10
RECRUITINGPhase 1NCT03460977

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and...

The purpose of this study is to learn about the safety and effects of the study medicine (called Mevrometostat) for the possible treatment of Relapsed/ Refractory Small Cell Lung...

Sponsor: PfizerEnrolling: 45320 locations
Metastatic Castration Resistant Prostate Cancer (mCRPC)Small Cell Lung Cancer (SCLC)Follicular Lymphoma (FL)
RECRUITINGPhase 3NCT06758401

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works...

The purpose of the study is to compare how the new combination treatment (Sigvotatug Vedotin plus pembrolizumab) works compared to pembrolizumab alone in patients with non-small...

Sponsor: PfizerEnrolling: 71420 locations
Non-Small Cell Lung CancerCarcinoma, Non-Small-Cell LungCarcinoma, Non-Small-Cell Lung (NSCLC)
RECRUITINGPhase 1NCT05355701

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07799933) administered as a single agent and in combination with other...

Sponsor: PfizerEnrolling: 26720 locations
MelanomaNon-Small-Cell Lung CancerThyroid Cancer+2
RECRUITINGPhase 1NCT07090499

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

The purpose of the study is to explore the safety and effects of the study drug (PF-08046876) in people diagnosed with advanced cancer of the bladder, lung, head and neck,...

Sponsor: PfizerEnrolling: 31020 locations
Advanced/Metastatic Solid TumorsBladder CancerUrothelial Carcinoma+10
RECRUITINGPhase 4NCT06952660

Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

TIVDAK is used for the treatment of cervical cancer that has come back after chemotherapy. Chemotherapy is a treatment that uses medicines to stop the growth of cancer cells. This...

Sponsor: PfizerEnrolling: 10020 locations
Cervical Cancer
RECRUITINGPhase 1NCT06995729

A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine

The purpose of the study is to learn about safety and how the body processes the study medicine called Zavegepant (PF-07930207) in children with a history of migraine. This study...

Sponsor: PfizerEnrolling: 1613 locations
Acute Treatment of Migraine
RECRUITINGNCT05046613

Observational Study to Assess Maternal, Fetal and Infant Outcomes Following Exposure to Rimegepant

The purpose of the study is to evaluate fetal, maternal, and infant outcomes through 12 months of age.

Sponsor: PfizerEnrolling: 7801 location
Migraine
RECRUITINGPhase 3NCT05156398

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

The purpose of this study is to compare the efficacy and safety of rimegepant to placebo as a preventative treatment for migraine in children and adolescents ≥ 6 to \<18 years...

Sponsor: PfizerEnrolling: 64020 locations
Migraine
RECRUITINGNCT06294925

A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis

The purpose of this real world non-interventional study is to learn about the effects of etrasimod as treatment for patients with moderate to severe ulcerative colitis. Patients...

Sponsor: PfizerEnrolling: 36020 locations
Colitis, Ulcerative
RECRUITINGNCT04338204

Observational Study To Assess The Effectiveness and Treatment Adherence Of Tofacitinib of Ulcerative Colitis In...

This is a prospective observational study using data from an existing, ongoing National Swedish registry (SWIBREG). This study is designed to assess the effectiveness and...

Sponsor: PfizerEnrolling: 12017 locations
Ulcerative Colitis
RECRUITINGNCT06398626

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

The purpose of this observational study is to learn about the effects of etrasimod as a treatment for adult patients with moderate to severe ulcerative colitis. Patients will be...

Sponsor: PfizerEnrolling: 30020 locations
Colitis, Ulcerative
RECRUITINGPhase 1NCT07400679

A Study to Learn How the Study Medicine Called PF-08653944 is Taken up Into the Blood in Adults With Overweight or...

This study is being done to learn how the study medicine affects the body and how safe it is for people who take it. The researchers will look at a number of health tests,...

Sponsor: PfizerEnrolling: 541 location
OverweightObesityHealthy
RECRUITINGNCT05890612

A Study on Paxlovid Once in the Market, to Observe Its Safety and Effectiveness in Patients Who Have a High Chance of...

The purpose of this study is to look at the safety and effectiveness of PAXLOVID in the real world and not in clinical studies. The study observes patients who have a high chance...

Sponsor: PfizerEnrolling: 30001 location
COVID-19
RECRUITINGPhase 3NCT05261139

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18...

The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and eliminated from your body after...

Sponsor: PfizerEnrolling: 16020 locations
COVID-19
RECRUITINGPhase 3NCT07013474

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

This is a Phase 3, randomized, actively controlled, double-blinded, double-dummy, superiority study to evaluate the efficacy and safety of ibuzatrelvir alone and in combination...

Sponsor: PfizerEnrolling: 30020 locations
COVID-19 Infection
RECRUITINGPhase 3NCT06866405

A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a...

This study aims to check how safe and well-tolerated a second dose of RSVpreF is when given during later pregnancies, and to see how long the immunity lasts from a single dose...

Sponsor: PfizerEnrolling: 55020 locations
RSV Infection
RECRUITINGPhase 2NCT07431853

A Study to Learn About mRNA Vaccines Against Influenza in Adults

The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune...

Sponsor: PfizerEnrolling: 77015 locations
Healthy Adults
RECRUITINGNCT05733104

A Study to Learn About the Study Medicine Zavicefta After it is Released Into the Markets in Korea

The purpose of this study is to learn about the safety and effectiveness of Zavicefta once released into the markets in Korea. This study is to learn about Zavicefta in patients...

Sponsor: PfizerEnrolling: 6001 location
Complicated Intra-abdominal InfectionComplicated Urinary Tract InfectionHospital-acquired Pneumonia
RECRUITINGPhase 2 / Phase 3NCT05431088

A Phase 2/3 Study in Adult and Adolescent Participants With SCD

The purpose of this study is to evaluate the safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of osivelotor.

Sponsor: PfizerEnrolling: 38920 locations
Sickle Cell Disease
RECRUITINGPhase 3NCT05145127

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

Study B7841007 is an open-label extension study to assess the long-term safety, tolerability, and efficacy of prophylaxis treatment with marstacimab in participants who did not...

Sponsor: PfizerEnrolling: 24520 locations
Hemophilia AHemophilia B
RECRUITINGPhase 3NCT05611801

A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called marstacimab) for the potential treatment of hemophilia in pediatric...

Sponsor: PfizerEnrolling: 10020 locations
Hemophilia AHemophilia B
RECRUITINGPhase 3NCT05568719

Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B...

A study to learn about the long-term safety and efficacy of giroctocogene fitelparvovec or fidanacogene elaparvovec in patients with hemophilia A or hemophilia B respectively, who...

Sponsor: PfizerEnrolling: 17316 locations
Hemophilia AHemophilia B
RECRUITINGPhase 1NCT06703606

A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.

The purpose of the study is to learn about safety, how the body processes marstacimab and how it works in patients with severe hemophilia A without inhibitors. Hemophilia A is...

Sponsor: PfizerEnrolling: 154 locations
Severe Hemophilia A