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Mild Cognitive Impairment Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

23 recruiting trials for Mild Cognitive Impairment. Eligibility criteria explained in plain English.

TrialFinderData lists 23 Mild Cognitive Impairment clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 1 is the largest group at 40% (2 studies); the largest phase groups are Phase 1: 2, Phase 1 / Phase 2: 1, Early Phase 1: 1, Phase 2: 1.

Research is led by VA Office of Research and Development (2), Manuel Montero Odasso (1), Rotman Research Institute at Baycrest (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is CpG1018 (drug, 3 trials), followed by MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark), Brainsway H1-Coil Deep TMS System.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
23
Total Trials
23
Recruiting Now
0
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT03020381

Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study

Motor slowing and cognitive slowing are more prevalent as we age. Importantly, the presence of both in an older person increases their risk of having dementia by ten times....

Sponsor: Manuel Montero OdassoEnrolling: 6001 location
RECRUITINGNCT03665831

Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults

In this study, the investigators will be examining the effects of the deep repetitive transcranial magnetic stimulation (rTMS) using the H1 coil in patients over the age of 60...

Sponsor: Rotman Research Institute at BaycrestEnrolling: 281 location
RECRUITINGNCT05151562

Music Therapy for Patients With Alzheimer's Disease

This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in...

Sponsor: Johns Hopkins UniversityEnrolling: 601 location
RECRUITINGPhase 1NCT04396873

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

Background: About 5 million adults in the U.S. have Alzheimer s disease or another adult-onset neurodegenerative disorder. Many studies have found that inflammation in the brain...

Sponsor: National Institute of Mental Health (NIMH)Enrolling: 1841 location
RECRUITINGNCT06993207

HOme-based Brain Monitoring With a GARment-EEG to Study Cognitive Decline in the Aging Population

This study will investigate the validity of the HOGAR EEG/PSG monitoring kit designed by Bitbrain as a tool for characterizing and assessing cognitive function in older adults, as...

Sponsor: BitbrainEnrolling: 5001 location
RECRUITINGNCT03140865

Wake Forest Alzheimer's Disease Clinical Core

Efforts to find treatments for AD have yielded only modest benefits, likely because longstanding AD pathological processes induce irreversible neurological compromise. These...

Sponsor: Wake Forest University Health SciencesEnrolling: 8501 location
RECRUITINGNCT04114994

Longitudinal Cognitive Assessment by BoCA

The Boston Cognitive Assessment (BoCA) is a self-administered online test intended for longitudinal cognitive monitoring. BoCA uses random not-repeating tasks to minimize learning...

Sponsor: Alzheimer's Light LLCEnrolling: 100001 location
RECRUITINGNCT05893524

Uppsala-Dalarna Dementia and Gait Project

UDDGait™ is a multidisciplinary research project with the overreaching goal of providing an aid for early identification of cognitive impairment and risk of dementia development,...

Sponsor: Dalarna UniversityEnrolling: 5502 locations
RECRUITINGNCT04124029

Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

This is a research study that aims to examine whether Veterans with mild Traumatic Brain Injuries are at risk for dementia by studying their memory, brain wave activity, brain...

Sponsor: VA Office of Research and DevelopmentEnrolling: 8001 location
RECRUITINGNCT05561205

rTMS for Apathy Clinical Trial

Apathy is a common, early, and disabling symptom in dementias and mild behavioural impairment such as Alzheimer's disease (AD) and is characterized by lack of interest and...

Sponsor: Sunnybrook Health Sciences CentreEnrolling: 101 location
RECRUITINGPhase 1NCT05606341

Innate Immunity Stimulation Via TLR9 in Early AD

This single-center, double-blind, placebo-controlled study will recruit in total 39 participants with either Mild Cognitive Impairment due to Alzheimer's disease (MCI) or Mild...

Sponsor: NYU Langone HealthEnrolling: 181 location
RECRUITINGNCT03025334

tDCS on Parkinson's Disease Cognition

Parkinson's disease (PD) has been classically regarded as a "movement disorder", so earlier work has focused on treating motor symptoms only. As PD patients now have longer life...

Sponsor: University of ManitobaEnrolling: 361 location
RECRUITINGPhase 1 / Phase 2NCT03836950

rTMS to Improve Cognition in Parkinson's

The purpose of this study is to examine safety, feasibility, and the behavioral and brain effects of a non-invasive treatment, repetitive transcranial magnetic stimulation (rTMS),...

Sponsor: VA Office of Research and DevelopmentEnrolling: 562 locations
RECRUITINGNCT05968703

Combined STN and NBM Deep Brain Stimulation for Mild Cognitive Impairment in Parkinson's Disease

The goal of this clinical trial is to evaluate the safety and tolerability of a novel deep brain stimulation (DBS) of the Subthalamic Nucleus (STN) and Nucleus Basalis of Meynert...

Sponsor: Helen M. Bronte-StewartEnrolling: 101 location
RECRUITINGNCT07504965

Dementia-friendly Apothecaries as a Resource for Mental Heath in the Elderly

The DARE study (Dementia-Friendly Apothecaries as a Resource for Mental Health in the Elderly) is a multicenter, prospective cohort study aiming to identify individuals with...

Sponsor: Ludwig-Maximilians - University of MunichEnrolling: 10201 location
RECRUITINGNCT07154394

Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease

This study seeks to explore the possible common pathogenesis of both cardiac amyloidosis and Alzheimer's disease, which can both be associated with amyloid deposits. Using...

Sponsor: University Hospital, EssenEnrolling: 151 location
RECRUITINGNCT03233646

Retinal Imaging in Neurodegenerative Disease

This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus...

Sponsor: Duke UniversityEnrolling: 20001 location
RECRUITINGNCT06897670

Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared...

The purpose of this research is to measure brain activity in individuals with mood disorders and memory problems using a simple, safe, and noninvasive method called functional...

Sponsor: Mayo ClinicEnrolling: 2001 location
RECRUITINGNCT05858008

Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment

This study will investigate the feasibility of implementing a time-restricted eating intervention in females with mild cognitive impairment. Targeted therapeutic interventions...

Sponsor: Julie PendergastEnrolling: 151 location
RECRUITINGNCT06733714

Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation...

BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological...

Sponsor: Universidade Federal do Rio de JaneiroEnrolling: 401 location
RECRUITINGEarly Phase 1NCT05138848

Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease

Dementia caused by Alzheimer's disease affects approximately 5.6 million adults over age 65, with costs expected to rise from $307 billion to $1.5 trillion over the next 30 years....

Sponsor: University of PittsburghEnrolling: 1161 location
RECRUITINGNCT07402356

VR Pupillometry in Cognitive Impairment

With disease-modifying therapies emerging for dementia and related conditions, identifying cognitive decline as early as possible is increasingly important. This prospective,...

Sponsor: Max-Planck-Institute of PsychiatryEnrolling: 1401 location
RECRUITINGPhase 2NCT07512362

Human Mesenchymal Stem Cells & Monoclonal Antibodies in the Treatment for Mild Cognitive Impairment or Early...

The purpose of this study is to test if adding one infusion of (Human Mesenchymal Stem Cells) hMSCs to the treatment with standard of care (SOC) monoclonal antibodies (mAb) will...

Sponsor: Bernard (Barry) BaumelEnrolling: 101 location

Frequently Asked Questions

There are currently 23 clinical trials for Mild Cognitive Impairment, with 23 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Mild Cognitive Impairment, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 0 Phase 3 trials for Mild Cognitive Impairment, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.