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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Updated June 2026 · ClinicalTrials.gov

Johns Hopkins University

Reviewed by TrialFinderData Editorial Team · Updated

35 clinical trials · 35 recruiting · OTHER

Johns Hopkins University has 35 clinical trials registered on ClinicalTrials.gov, with 35 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Johns Hopkins University\'s Trial Portfolio

Johns Hopkins University is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

35 of Johns Hopkins University's 35 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Johns Hopkins University's research footprint spans Alzheimer Disease (3 trials), Bladder Cancer (2), and Ischemic Stroke (2) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Not Applicable is the largest single phase in Johns Hopkins University's portfolio at 54% of registered trials. The full phase breakdown appears in the sidebar.

Trials by Johns Hopkins University

RECRUITINGNCT05672615

Mood Alterations in the Patients With Non-Muscle Invasive Bladder Cancer Treated With BCG

The purpose of this study is to evaluate mood changes in patients with Non-Muscle Invasive Bladder Cancer who are receiving intravesical Bacillus Calmete-Guerin (BCG). Patients...

Sponsor: Johns Hopkins UniversityEnrolling: 421 location
Non-Muscle Invasive Bladder Cancer
RECRUITINGNCT05649306

Gender Related Coping and Survivorship for Genitourinary Cancers

This research is being done to learn more about coping and survivorship of women with bladder cancer, specifically regarding psychosocial distress and sexual dysfunction. This...

Sponsor: Johns Hopkins UniversityEnrolling: 802 locations
Bladder Cancer
RECRUITINGNCT05792722

Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy

The purpose of this clinical trial is to determine if prostate-capsule-sparing cystectomy improves functional outcomes without comprising oncologic outcomes in male patients...

Sponsor: Johns Hopkins UniversityEnrolling: 702 locations
Bladder Cancer
RECRUITINGNCT05151562

Music Therapy for Patients With Alzheimer's Disease

This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in...

Sponsor: Johns Hopkins UniversityEnrolling: 601 location
Mild Cognitive ImpairmentAlzheimer Disease
RECRUITINGNCT06930560

HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms

This randomized controlled trial study aims to evaluate a revised hearing care intervention for older adults with Alzheimer's Disease and Related Dementias (ADRD). The...

Sponsor: Johns Hopkins UniversityEnrolling: 3001 location
Alzheimer DiseaseDementiaHearing Loss+1
RECRUITINGNCT03799991

Vestibular Therapy in Alzheimer's Disease

Nearly 2 out of 3 patients with Alzheimer's disease (AD) experience problems with balance and mobility, which places such patients at increased risk of falling. The vestibular...

Sponsor: Johns Hopkins UniversityEnrolling: 1001 location
Vestibular DiseasesVestibular DisorderAlzheimer Disease
RECRUITINGNCT07521930

Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)

The goal of this clinical trial is to evaluate the safety and preliminary efficacy of an implantable device that records and stimulates different areas of the brain to allow...

Sponsor: Johns Hopkins UniversityEnrolling: 51 location
Tetraplegia/TetraparesisAmyotrophic Lateral Sclerosis (ALS)Muscular Disorders, Atrophic+6
RECRUITINGNCT07223008

Bilateral Embolization of the Middle Meningeal Arteries for Refractory Chronic Migraine

This study is to test the safety and feasibility of a procedure called embolization of the middle meningeal arteries (MMA), using a product called Onyx. Embolization creates a...

Sponsor: Johns Hopkins UniversityEnrolling: 131 location
MigraineChronic Migraine HeadacheRefractory Migraine
RECRUITINGPhase 2NCT06718413

Myofascial Dysfunction in Post Stroke Shoulder Pain

Shoulder pain is extremely common after stroke and occurs in 30-70% of patients. The pain may begin as early as one week after stroke, although peak onset and severity occurs...

Sponsor: Johns Hopkins UniversityEnrolling: 681 location
Stroke
RECRUITINGNCT06899711

External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients

Patients that undergo decompressive craniectomy are at risk of delayed changes in brain function known as "Sunken Flap Syndrome" or "Syndrome of the Trephined." The goal of this...

Sponsor: Johns Hopkins UniversityEnrolling: 722 locations
CraniectomyTrephined SyndromeTraumatic Brain Injury (TBI) Patients+1
RECRUITINGNCT04164641

Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot...

Determining whether the utilization of Noraxon myoRESEARCH Software gait analysis Evaluation and orthotic gait Correction can reduce diabetic foot ulceration Or subsequent...

Sponsor: Johns Hopkins UniversityEnrolling: 691 location
Diabetic Foot Ulcer
RECRUITINGNCT06364644

Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure

This study aims to determine whether a 6-month multilevel intervention involving problem-solving training, exercise training and support from community health workers is more...

Sponsor: Johns Hopkins UniversityEnrolling: 2102 locations
Type2diabetesHeart FailureObesity
RECRUITINGNCT00733590

Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention

The overall hypothesis of this study is that subtle interactions between structural (substrate) and functional (trigger) abnormalities of the heart, some of which are...

Sponsor: Johns Hopkins UniversityEnrolling: 15004 locations
Heart Failure, CongestiveDeath, Sudden, CardiacArrhythmia+1
RECRUITINGNCT06308094

320-detector Computed Tomography to Assess Myocardial Extracellular Volume Fraction in Patients With Atrial...

This study explores the relationship between myocardial fibrosis and patient outcomes in Atrial Fibrillation (AF), specifically after catheter ablation. It aims to use Cardiac CT,...

Sponsor: Johns Hopkins UniversityEnrolling: 1001 location
Atrial Fibrillation
RECRUITINGNCT01076660

Left Ventricular Structural Predictors of Sudden Cardiac Death

Sudden cardiac death (SCD) poses a significant health care challenge with high annual incidence and low survival rates. Implantable cardioverter defibrillators (ICDs) prevent SCD...

Sponsor: Johns Hopkins UniversityEnrolling: 4002 locations
Ischemic CardiomyopathyNonischemic Cardiomyopathy
RECRUITINGPhase 4NCT04781972

Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHD

The investigators' goal is to develop neuroimaging biomarkers to predict response to treatment with methylphenidate, which then can be used in the development of novel...

Sponsor: Johns Hopkins UniversityEnrolling: 301 location
ADHD - Combined Type
RECRUITINGNCT06861868

Brain and Behavior Influences on Obesity Development From Infancy Through Childhood

The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and...

Sponsor: Johns Hopkins UniversityEnrolling: 2104 locations
Obesity and Overweight
RECRUITINGPhase 1NCT06660381

Psilocybin-assisted Treatment for Cannabis Use Disorder

This pilot study will evaluate the therapeutic potential of psilocybin in people with Cannabis Use Disorder (CUD). This study will examine the impact of psilocybin treatment on...

Sponsor: Johns Hopkins UniversityEnrolling: 121 location
Cannabis Use Disorder
RECRUITINGNCT05703386

Imaging the Pathogenesis of Cerebral Small Vessel Disease

Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter...

Sponsor: Johns Hopkins UniversityEnrolling: 501 location
Ischemic StrokeHypertensionHyperlipidemias+1
RECRUITINGNCT05845021

Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty

The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty. The main question this study aims...

Sponsor: Johns Hopkins UniversityEnrolling: 20001 location
OsteoporosisArthroplasty ComplicationsFragility Fracture
RECRUITINGPhase 4NCT05704036

Estrogen Supplementation and Bone Health in Women With CF

The goal of this study is to learn about the role of estrogen and other hormones in bone development in adolescent and young adult women with cystic fibrosis (CF). The study has...

Sponsor: Johns Hopkins UniversityEnrolling: 751 location
Cystic FibrosisHypoestrogenism
RECRUITINGPhase 2NCT07059091

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

This research is being done to test if a drug called omalizumab can help people with Chronic Obstructive Pulmonary Disease (COPD) and allergies. Each participant will be in the...

Sponsor: Johns Hopkins UniversityEnrolling: 33420 locations
Chronic Obstructive Pulmonary Disease (COPD)Allergies
RECRUITINGPhase 2NCT06587256

Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea.

Snoring is a common problem caused by vibration of tissues in the throat region during sleep. Although snoring is sometimes dismissed as a minor nuisance rather than a medical...

Sponsor: Johns Hopkins UniversityEnrolling: 1001 location
Mild Obstructive Sleep ApneaSnoring
RECRUITINGNCT05022862

Economic Incentives and vDOT for Latent Tuberculosis Infection

The purpose of this study is to evaluate a novel and scalable intervention that combines Video Directly Observed Therapy (vDOT) and financial incentives to promote completion of...

Sponsor: Johns Hopkins UniversityEnrolling: 3991 location
Latent Tuberculosis
RECRUITINGPhase 3NCT06253715

Shortened Regimen for Drug-susceptible TB in Children

While drug-susceptible tuberculosis (TB) disease in children currently requires four to six months of treatment, most children may be able to be cured with a shorter treatment of...

Sponsor: Johns Hopkins UniversityEnrolling: 8609 locations
TuberculosisTuberculosis, PulmonaryTuberculosis, Lymph Node+1
RECRUITINGNCT05285202

Clinic-based Versus Hotspot-focused Active TB Case Finding

This five-year study will evaluate two strategies for conducting tuberculosis (TB) active case finding (ACF) and linkage to TB treatment or TB preventive therapy (TPT) in...

Sponsor: Johns Hopkins UniversityEnrolling: 1500001 location
Tuberculosis, PulmonaryMycobacterium Tuberculosis Infection
RECRUITINGPhase 3NCT06497465

Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB Treatment

This will be a Phase IIIb Clinical Trial, an international multicenter, randomized, three-arm, non-comparative trial of efficacy, safety, and tolerability of the dual therapy...

Sponsor: Johns Hopkins UniversityEnrolling: 1506 locations
TuberculosisHIV
RECRUITINGNCT05171478

Full-Field Optical Coherence Tomography (FFOCT) for Evaluation of Bronchoscopic Small Biopsy Specimens

This study sets out to register imaging of small biopsy specimens obtained during bronchoscopy using full-field optical coherence tomography against standard histologic evaluation.

Sponsor: Johns Hopkins UniversityEnrolling: 201 location
Lung CancerSarcoidosis
RECRUITINGNCT06408142

Universal Test and Connect for HIV Service Delivery in South Africa

The goal of this study is to determine how many patients with HIV or at high risk of getting HIV attend the Emergency Department (ED) in South Africa (SA). The investigators will...

Sponsor: Johns Hopkins UniversityEnrolling: 20001 location
Human Immunodeficiency VirusPre-Exposure ProphylaxisEmergency Department+1
RECRUITINGNCT06027671

Structured Peer-delivered ART and Reentry Community Strategy

The overarching goal of this study is to implement a transition community adherence club strategy (Full-SPARCS) for HIV-positive individuals transitioning from correctional to...

Sponsor: Johns Hopkins UniversityEnrolling: 4001 location
Retention in Care

Showing 30 of 35 trials. The remainder are accessible through individual condition pages or directly on ClinicalTrials.gov.

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Johns Hopkins University have on ClinicalTrials.gov?

Johns Hopkins University has 35 clinical trials registered on the federal ClinicalTrials.gov registry, of which 35 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Johns Hopkins University study?

Johns Hopkins University's registered trials cover 20 conditions on ClinicalTrials.gov, led by Alzheimer Disease (3 trials), Bladder Cancer (2 trials), Ischemic Stroke (2 trials), Tuberculosis (2 trials), Tuberculosis, Pulmonary (2 trials). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Johns Hopkins University clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 35 trials tracked for Johns Hopkins University.