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Non-cystic Fibrosis Bronchiectasis Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

13 recruiting trials for Non-cystic Fibrosis Bronchiectasis. Eligibility criteria explained in plain English.

TrialFinderData lists 13 Non-cystic Fibrosis Bronchiectasis clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 2 is the largest group at 38% (3 studies); the largest phase groups are Phase 2: 3, Phase 3: 2, Phase 1: 2, Phase 4: 1.

Research is led by Assiut University (2), Haisco Pharmaceutical Group Co., Ltd. (2), CSL Behring (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Placebo (drug, 3 trials), followed by HSK31858, tablet, CSL787.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
13
Total Trials
13
Recruiting Now
2
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT07599839

BASE: Bronchiectasis Severity and Exacerbation Risk Study

Non-cystic fibrosis bronchiectasis (NCFB) is a chronic airway disease characterized by permanent bronchial dilatation, impaired mucus clearance, recurrent infection, airway...

Sponsor: Assiut UniversityEnrolling: 7501 location
RECRUITINGPhase 2NCT07048262

Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults With Non-cystic Fibrosis Bronchiectasis...

This study is a phase 2b, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose range finding study designed to explore the efficacy, safety, and...

Sponsor: CSL BehringEnrolling: 45013 locations
RECRUITINGPhase 3NCT07616375

A Study to Assess the Safety of HSK31858 in Participants With Non-Cystic Fibrosis Bronchiectasis

This is a phase III, single-arm, open-label, multicenter study to assess the safety of HSK31858 in non-cystic fibrosis bronchiectasis (NCFBE) participants.

Sponsor: Haisco Pharmaceutical Group Co., Ltd.Enrolling: 6691 location
RECRUITINGPhase 2NCT06559150

A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

This study is a randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of ensifentrine inhalation suspension (3 mg) delivered twice daily...

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USAEnrolling: 28420 locations
RECRUITINGPhase 1NCT06603246

A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease

This study evaluates the safety, tolerability, and activity of inhaled GDC-6988 in participants with muco-obstructive disease.

Sponsor: Genentech, Inc.Enrolling: 1287 locations
RECRUITINGPhase 1NCT07289464

A Clinical Study of RSS0343 in Healthy Subjects

This is a phase I study to evaluate the safety, tolerability and pharmacokinetics of RSS0343 following multiple oral doses in healthy subjects, as well as its effects on the...

Sponsor: Reistone Biopharma Company LimitedEnrolling: 481 location
RECRUITINGNCT07599969

Bronchiectasis Phenotype Identification Model

The Bronchiectasis Phenotype Identification Model (BPIM) is a prospective observational development-validation study within the Assiut University bronchiectasis translational...

Sponsor: Assiut UniversityEnrolling: 7501 location
RECRUITINGPhase 3NCT06660992

A Study to Assess the Efficacy and Safety of HSK31858 in Participants With Non-Cystic Fibrosis Bronchiectasis

This is a phase III, randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of HSK31858 in non-cystic fibrosis bronchiectasis (NCFBE)...

Sponsor: Haisco Pharmaceutical Group Co., Ltd.Enrolling: 6692 locations
RECRUITINGPhase 4NCT06242795

Hypertonic Saline in NCFB

The purpose of this single arm clinical trial is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on clearance of mucus from the lungs in people with...

Sponsor: University of North Carolina, Chapel HillEnrolling: 201 location
RECRUITINGNCT06487273

Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis

Bronchiectasis is a chronic lung disease of multiple aetiologies characterised by permanent dilatation of the calibre of a territory of the bronchial tree with impaired...

Sponsor: Physio-AssistEnrolling: 62220 locations
RECRUITINGNCT07245407

A Translational Study for Phenotyping and Endotyping Chinese Patients With NCFBE

Non-cystic fibrosis bronchiectasis (NCFBE) is a chronic respiratory disease characterized by a clinical syndrome of chronic productive cough and recurrent respiratory infections in...

Sponsor: AstraZenecaEnrolling: 32020 locations
RECRUITINGNCT05860803

Breathing Training and Exercise Capacity in Non-CFB

The purpose of this research is to investigate whether a home-based and health coach supported specific breathing and respiratory muscle training program improves the ability to...

Sponsor: Mayo ClinicEnrolling: 501 location
RECRUITINGPhase 2NCT07547436

A Study to Access Activity and Safety With SAR445399 Compared With Placebo in Participants Aged 18 to 80 Years of Age...

This is a randomized, double-blind, placebo-controlled study to measure the reduction in mucus plug score at 24 weeks of treatment with SAR445399 compared with placebo in adult...

Sponsor: SanofiEnrolling: 704 locations

Frequently Asked Questions

There are currently 13 clinical trials for Non-cystic Fibrosis Bronchiectasis, with 13 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Non-cystic Fibrosis Bronchiectasis, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 2 Phase 3 trials for Non-cystic Fibrosis Bronchiectasis, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.