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Osteosarcoma Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

13 recruiting trials for Osteosarcoma. Eligibility criteria explained in plain English.

TrialFinderData lists 13 Osteosarcoma clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 1 is the largest group at 71% (5 studies); the largest phase groups are Phase 1: 5, Phase 1 / Phase 2: 1, Phase 2: 1.

Research is led by Istituto Ortopedico Rizzoli (2), University of Florida (1), Memorial Sloan Kettering Cancer Center (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is standard of care biopsy (other, 2 trials), followed by Toronto Extremity Salvage Score, Musculoskeletal Tumor Society Score.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
13
Total Trials
13
Recruiting Now
0
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT00411060

Clinical Orthopaedic Data Bank (Acute and Chronic)

Data involving orthopaedic conditions and rehabilitation aspects of musculoskeletal and neuromuscular disorders will be collected and stored as part of the normal clinical care of...

Sponsor: University of FloridaEnrolling: 100001 location
RECRUITINGNCT05779670

Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery

The objective of this study is to describe adherence to a personalised home exercise program in patients undergoing resection and reconstruction of lower limb for bone tumor and...

Sponsor: Istituto Ortopedico RizzoliEnrolling: 501 location
RECRUITINGNCT03442465

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

The purpose of this study is to look at the amount of function that returns in participants that have reconstruction with bone graft or artificial device and in participants who...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 3005 locations
RECRUITINGPhase 1NCT02508038

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid...

This phase I trial studies the safety of transplantation with a haploidentical donor peripheral blood stem cell graft depleted of TCRαβ+ cells and CD19+ cells in conjunction with...

Sponsor: University of Wisconsin, MadisonEnrolling: 221 location
RECRUITINGNCT06017518

An Observational Study of Local Relapse After High Grade Osteosarcoma

multicenter retrospective and prospective study in patients with high-grade osteosarcoma

Sponsor: Istituto Ortopedico RizzoliEnrolling: 1502 locations
RECRUITINGNCT06029218

Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy

Thanks to the intrinsic qualities of the proton beam, proton therapy will reduce adverse effects of irradiation. The Proteus®One is the latest generation of proton therapy...

Sponsor: Centre Antoine LacassagneEnrolling: 1061 location
RECRUITINGPhase 1NCT07052383

Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas

This is a open-Label, dose-escalation study to evaluate the safety, tolerability and antitumor activity of DIT309 in subjects with advanced bone and soft tissue sarcomas.The study...

Sponsor: Tcelltech Inc.Enrolling: 151 location
RECRUITINGPhase 1NCT06500819

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors

The purpose of this study is to test the manufacturing feasibility and safety of intravenous (IV) administration of B7-H3CART in children and young adult subjects with relapsed...

Sponsor: Stanford UniversityEnrolling: 411 location
RECRUITINGPhase 1 / Phase 2NCT05588648

Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive...

MP-VAC-209 is a Phase I/II, open label, single arm, multi-center study to assess safety, tolerability, and antitumor activity of vactosertib as a single agent in adolescents and...

Sponsor: MedPacto, Inc.Enrolling: 483 locations
RECRUITINGNCT06064682

An Organoid-based Functional Precision Medicine Trial in Osteosarcoma

The purpose of this study is to examine if we can predict sensitivity of osteosarcoma to different chemotherapy agents using tissue cultures in the laboratory. We know that...

Sponsor: Jonsson Comprehensive Cancer CenterEnrolling: 401 location
RECRUITINGPhase 1NCT07648069

Tumor Neoantigen Vaccine SarVac Combined With Tumor Specific Lymphocyte Reinfusion in the Treatment of Advanced Sarcoma

The primary objective of this trial is to evaluate the safety and tolerability of the tumor neoantigen vaccine (SarcVac) in combination with a PD-1 antibody, with or without...

Sponsor: Sun Yat-sen UniversityEnrolling: 161 location
RECRUITINGPhase 2NCT06638931

Agnostic Therapy in Rare Solid Tumors

The ANTARES study is a phase II basket trial designed to evaluate the tissue-agnostic efficacy of the monoclonal anti-PD1 antibody, nivolumab, in patients with advanced or...

Sponsor: Instituto do Cancer do Estado de São PauloEnrolling: 288 locations
RECRUITINGPhase 1NCT03721068

Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or...

The body has different ways of fighting infections and disease. No single way seems perfect for fighting cancer. This research study combines two different ways of fighting...

Sponsor: UNC Lineberger Comprehensive Cancer CenterEnrolling: 182 locations

Frequently Asked Questions

There are currently 13 clinical trials for Osteosarcoma, with 13 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Osteosarcoma, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 0 Phase 3 trials for Osteosarcoma, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.