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Memorial Sloan Kettering Cancer Center

27 clinical trials · 27 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Memorial Sloan Kettering Cancer Center

RECRUITINGPhase 1NCT06246968

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

Participants will have a confirmed diagnosis of metastatic breast cancer and will receive pembrolizumab in combination with cryoablation OR pembrolizumab alone. Participants will...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 307 locations
Metastatic Breast CancerBreast CancerBreast Cancer Stage IV+5
RECRUITINGPhase 2NCT07218601

Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung Cancer

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure changes in certain chemicals in the...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 607 locations
Non-Small Cell Lung Cancer
RECRUITINGPhase 1NCT06807632

A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer

This study will test whether valemetostat in combination with atezolizumab is a safe treatment that causes few or mild side effects in people with extensive-stage small cell lung...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 247 locations
Extensive-stage Small-cell Lung Cancer
RECRUITINGPhase 1NCT04167969

The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer

The purpose of this study is to see whether using the copper-64 (64Cu) or zirconium-89 (89Zr) radiolabeled PSMA-targeting C' dot tracer, termed 64Cu-NOTA-PSMAi-PEG-Cy5.5-C' dots...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 162 locations
Prostate Cancer
RECRUITINGPhase 2NCT06594991

A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

The purpose of this study is to test whether the combination of fianlimab, cemiplimab, and ipilimumab is a safe and effective treatment that causes few or mild side effects for...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 8811 locations
Advanced Melanoma
RECRUITINGPhase 1NCT05859074

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

Participants of this study will have a diagnosis of a solid tumor cancer that has come back to its original location or spread beyond its original location (advanced), came back...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 567 locations
Cutaneous Squamous Cell CarcinomaSCC - Squamous Cell CarcinomaBasal Cell Carcinoma+16
RECRUITINGNCT07052916

A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties

Research has shown that music-based activities may help improve brain functions, such as attention, memory, and executive function. Because of this past research, the researchers...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 607 locations
Blood CancerLymphomaLeukemia+1
RECRUITINGPhase 2NCT06561360

A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)

The researchers are doing this study to compare the safety of vemurafenib in combination with obinutuzumab to the standard of approach of cladribine in combination with rituximab....

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 8610 locations
Hairy Cell Leukemia
RECRUITINGNCT04668872

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

The purpose of this study is to study the way radioembolization works by collecting biopsy samples of participants' tumors after the procedure. This research may improve the way...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 801 location
Colon Cancer Liver MetastasisColon CancerAdenocarcinoma of the Colon+3
RECRUITINGPhase 2NCT05985161

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

The purpose of this study is to find out whether selinexor is an effective treatment for people who have a relapsed/refractory Wilms tumor, rhabdoid tumor, MPNST, or another solid...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 4515 locations
Wilms TumorRhabdoid TumorMalignant Peripheral Nerve Sheath Tumors+4
RECRUITINGPhase 2NCT05239624

Enfortumab Vedotin and Pembrolizumab in People With Bladder Cancer

This study will test whether enfortumab vedotin combined with pembrolizumab is an effective treatment for people with bladder cancer (urothelial carcinoma) involving the lymph...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 2310 locations
Urothelial Carcinoma
RECRUITINGPhase 3NCT06929286

A Study Comparing Standard Treatments in People With Non-Muscle Invasive Bladder Cancer (NMIBC)

The purpose of this study is to compare the effectiveness of different FDA-approved/NCCN-recommended drug treatments for NMIBC. In particular, the FDA-approved drug nadofaragene...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 1251 location
Non-Muscle Invasive Bladder Cancer
RECRUITINGNCT05733013

A Study to Collect Information About the Use of Redifferentiating Medications as a Standard Treatment for Thyroid Cancer

The purpose of this study to learn more about the use of redifferentiating medications as a standard treatment for radioactive iodine/RAI-refractory thyroid cancer. This study is...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 1001 location
Thyroid CancerThyroidRefractory Thyroid Cancer
RECRUITINGNCT03483337

New MRI Biomarkers in Head and Neck Cancers

Magnetic resonance imaging (MRI) is a diagnostic technique that takes pictures of organs of the body. It uses magnetic fields and radio waves that cannot be felt. This makes...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 2001 location
Head and Neck CancerThyroid Cancer
RECRUITINGPhase 2NCT06007924

A Study of Avutometinib and Defactinib in People With Thyroid Cancer

The researchers are doing this study to find out if the combination of avutometinib and defactinib is an effective treatment for RAF dimer-driven radioiodine-refractory...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 307 locations
Thyroid Cancer
RECRUITINGPhase 2NCT06123338

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

The purpose of this study to find out whether adding trastuzumab and pembrolizumab to standard chemotherapy is an effective treatment for resectable HER2+ esophagogastric cancer.

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 4910 locations
Esophageal CancerGastric AdenocarcinomaHER2 Gene Mutation
RECRUITINGNCT06558786

Registry for Esophageal and Gastroesophageal Junction Cancer

The purpose of this registry study is to create a database-a collection of information-for better understanding standard treatments for esophageal and Gastroesophageal Junction...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 501 location
Gastroesophageal-junction CancerEsophageal Cancer
RECRUITINGPhase 2NCT07063212

A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)

The purpose of this study to find out whether sacituzumab govitecan in combination with cetuximab is an effective and safe treatment approach for people with recurrent and/or...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 407 locations
Squamous Cell Carcinoma of Head and NeckSinus CancerNasal Cavity Cancer+9
RECRUITINGEarly Phase 1NCT05093335

In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

The purpose of this study is to determine the uptake of the imaging agent \[68Ga\]-pentixafor with PET/CT scans in people with monoclonal gammopathy of undetermined significance...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 301 location
Non-Hodgkin LymphomaMultiple MyelomaHistiocytic Neoplasms+2
RECRUITINGPhase 1 / Phase 2NCT04577014

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

This study is being done to find out whether the study drug Retifanlimab, a monoclonal antibody against the PD-1 protein, combined with gemcitabine and docetaxel, is a safe and...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 981 location
Soft Tissue SarcomaSarcoma,Soft TissueSarcoma+1
RECRUITINGPhase 2NCT07089992

A Study of Pembrolizumab in People With Ultra-Rare Sarcomas

The purpose of the study is to find out if pembrolizumab is a useful treatment that causes few or mild side effects in people with ultra-rare sarcoma. The researchers will also...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 326 locations
Sarcoma
RECRUITINGPhase 1NCT06021626

A Study of CRD3874-SI in People With Solid Tumors

This study will test the safety of a study drug called CRD3874-SI. The researchers will test different doses of CRD3874-SI to find the highest dose that causes few or mild side...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 727 locations
SarcomaMerkel Cell Carcinoma
RECRUITINGPhase 2NCT06477419

A Study of Sacituzumab Govitecan in People With Mesothelioma

Participants will receive sacituzumab govitecan until their disease gets worse (progresses), they have severe side effects and cannot continue study treatment, or the participants...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 337 locations
MesotheliomaMesotheliomas PleuralMesothelioma; Pleura
RECRUITINGPhase 2NCT06057935

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

The purpose of this study is to find out whether intraperitoneal or intravenous chemotherapy given after cytoreductive surgery and HIPEC are effective treatments for people with...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 6413 locations
Malignant Peritoneal MesotheliomaPeritoneal MesotheliomaMesothelioma+2
RECRUITINGNCT06037941

Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural Mesothelioma

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure how people respond to standard...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 207 locations
Malignant Pleural Mesothelioma
RECRUITINGNCT07399977

Using a Blood Test and Software Tool to Guide Treatment for Venous Thromboembolism

The purpose of this study is to find out whether a software tool, ctDNA/VTE (Venous Thromboembolism) risk score model, is an effective way to predict the likelihood of VTE coming...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 2598 locations
Venous ThromboembolismDeep Venous Thrombosis
RECRUITINGNCT07144800

Family COMIDA (Consumo de Opciones Más Ideales De Alimentos) (Eating More Ideal Food Options)

The purpose of this study is to determine the most effective family-centered intervention (FCI) for weight loss and obesity prevention in Hispanic families. FCI is a type of...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 13191 location
ObesityChild ObesityWeight Loss