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Rheumatoid Arthritis (RA) Clinical Trials

26 recruiting trials for Rheumatoid Arthritis (RA). Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
26
Total Trials
26
Recruiting Now
0
Phase 3 Trials
10
Sponsors

Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT07034196

Comparative Effectiveness of Primary Care Providers Trained in Rheumatoid Arthritis Management Versus Rheumatologist...

Rheumatoid arthritis (RA) is a complex autoimmune disease where the immune system attacks healthy joint tissue; causing pain, swelling, and stiffness of the joints. This disease...

Sponsor: St. Lawrence Health SystemEnrolling: 1001 location
RECRUITINGPhase 1NCT07245992

A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis

The aim of this study is to evaluate the safety of F8IL10 when administered by intra-articular injection and to determine the maximum tolerated dose (MTD) in order to establish...

Sponsor: Philogen S.p.A.Enrolling: 422 locations
RECRUITINGNCT06630715

Efficacy Of Upadacitinib In Psoriatic Arthritis And Comparison To Rheumatoid Arthritis.

The general objective of the OPTIMA study is to assess the time course and interrelationship of imaging (ultrasound and magnetic resonance imaging), clinical, laboratory, and...

Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioEnrolling: 17814 locations
RECRUITINGPhase 1NCT07258849

A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis

The purpose of this study is to evaluate how well LY4213663 is tolerated and what side effects may occur in healthy participants and participants with rheumatoid arthritis (RA)....

Sponsor: Eli Lilly and CompanyEnrolling: 1349 locations
RECRUITINGNCT07484243

Clinical Cohort Construction and Therapeutic Effect Evaluation of Integrated Traditional Chinese and Western Medicine...

This is a large-scale, multicenter observational study on the treatment of rheumatoid arthritis (RA) with integrated Traditional Chinese and Western medicine. The study plans to...

Sponsor: Yuanyuan ZhangEnrolling: 100001 location
RECRUITINGNCT07138729

Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis

This study proposes to evaluate 99mTc-CTR-FAPI SPECT imaging as a cost-effective, low-radiation, and widely accessible alternative to 68Ga-FAPI PET/CT for assessing synovial...

Sponsor: Luo YapingEnrolling: 201 location
RECRUITINGPhase 1NCT06994143

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Rheumatoid Arthritis

A Phase I, open-label study of CLN-978 in patients with treatment-refractory rheumatoid arthritis.

Sponsor: Cullinan Therapeutics Inc.Enrolling: 372 locations
RECRUITINGNCT07277491

Assessment of Nutritional Status in Rheumatic Diseases and Association to Disease Activity

The aim of the present work is to assess the nutritional status among different rheumatic diseases patients and to study its association with the corresponding diseases activity.

Sponsor: Cairo UniversityEnrolling: 4601 location
RECRUITINGPhase 2NCT06671054

A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying...

The study is a randomized, double blind, placebo-controlled, dose response, phase II, multicentre trial to evaluate the efficacy and safety of oral AP1189 administered at the...

Sponsor: SynAct Pharma ApsEnrolling: 24011 locations
RECRUITINGPhase 1NCT06628206

Safety and Pharmacokinetics of LPX-TI641 in Rheumatoid Arthritis and Psoriatic Arthritis

The goal of this clinical trial is to study the drug LPX-TI641 in patients with rheumatoid arthritis and psoriatic arthritis. We will compare the safety and tolerability of...

Sponsor: LAPIX Therapeutics Inc.Enrolling: 481 location
RECRUITINGNCT06693479

Could a Feedback Device Help Manage Work-related Shoulder Disorders?

Work-related shoulder pain is a common problem with significant socio-economic repercussions. The impact of these disorders on workers is considerable, particularly in terms of...

Sponsor: Laval UniversityEnrolling: 421 location
RECRUITINGPhase 1NCT07182656

Safety, Tolerability, and PK/PD of CIGB-814 in Chinese Health Participants

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of CIGB-814 for injection after single and multiple administrations in healthy...

Sponsor: Yi FangEnrolling: 701 location
RECRUITINGNCT06779123

Treatment With Auricular Vagus Nerve Stimulation in Rheumatoid Arthritis - the TRAVAGA Study

Purpose and aim The overall aim is to investigate efficacy and safety of a newly developed non-invasive auricular investigational device that electrically stimulates the...

Sponsor: taVNS ABEnrolling: 1286 locations
RECRUITINGNCT07264101

Validity And Reliability Of The Four Square Step Test In Individuals With Rheumatoid Arthritis

This cross-sectional observational study aims to evaluate the validity and reliability of the Four Square Step Test (FSST) in individuals with rheumatoid arthritis. In addition,...

Sponsor: Inonu UniversityEnrolling: 501 location
RECRUITINGNCT07123038

A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T...

To assess the emergence, type, severity, and potential causality of delayed adverse events following administration of a gene-modified Treg therapeutic.

Sponsor: Sonoma Biotherapeutics, Inc.Enrolling: 3610 locations
RECRUITINGNCT06889415

Rheumatoid Arthritis and Osteosarcopenia: Associated Factors

Our study is a cross-sectional study, and its aim is to compare and analyze the prevalence of sarcopenia and osteoporosis in patients with rheumatoid arthritis (RA) with a control...

Sponsor: Konya Beyhekim Training and Research HospitalEnrolling: 2001 location
RECRUITINGNCT07304505

Probiotics in Adults With Rheumatoid Arthritis

The goal of this clinical study is to collect data on the effect of probiotic administration on clinical outcomes in rheumatoid arthritis patients. Participants will: * Have a...

Sponsor: Ancilia BiosciencesEnrolling: 501 location
RECRUITINGPhase 1NCT06946641

A Phase I Study of QLS12010 Capsules: Safety, Tolerability, PK, PD, and Food Effects in Healthy Adults and Moderate to...

The goal of this clinical trial is to evaluate the safety, tolerability, PK, and PD of single and multiple ascending doses of QLS12010 Capsules and the effect of food on their PK...

Sponsor: Shanghai Qilu Pharmaceutical Research and Development Center LTDEnrolling: 1021 location
RECRUITINGPhase 1NCT06647069

A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic Diseases

This is an open-label, multi-ascending dose (MAD) phase 1 study, with dose expansion at selected doses, in adult patients with select autoimmune rheumatic diseases including...

Sponsor: SanofiEnrolling: 628 locations
RECRUITINGNCT07463937

A RWS of SC MTX in Chinese RA Patients

Design: A prospective, single-arm, multicenter, real-world study that does not interfere with the patient's treatment plan Primary Objective: 1\. To evaluate the effectiveness...

Sponsor: Peking University People's HospitalEnrolling: 100001 location
RECRUITINGNCT07150000

Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy

The CARe RAiSE project represents a pioneering translational initiative aimed at advancing precision medicine in the treatment of autoimmune rheumatic diseases. The primary...

Sponsor: University of BonnEnrolling: 1201 location
RECRUITINGNCT07403188

A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101

The purpose of this long-term follow-up (LTFU) study is to collect delayed adverse events (AEs) and understand the persistence of KYV-101 (autologous CAR T cell product;...

Sponsor: Kyverna TherapeuticsEnrolling: 701 location
RECRUITINGPhase 1NCT07085676

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

A Phase 1 study of HBI0101 BCMA-CART in B-Cell Mediated Autoimmune Rheumatic Diseases. The goal of the study is evaluation of safety and identification of the maximum HBI0101 CART...

Sponsor: Polina StepenskyEnrolling: 601 location
RECRUITINGNCT06880653

Dose Response of Exercise for Arthritis Management

The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.

Sponsor: University of South CarolinaEnrolling: 2851 location
RECRUITINGNCT06696027

AYLo - AutoimmunitY and Loss of y

The AYLo study (AutoimmunitY and Loss of y - Investigating the Role of Hematopoietic Mutations and Mosaic Mutation in the Y Chromosome in Autoimmune Rheumatologic Diseases) aims...

Sponsor: University of BonnEnrolling: 5001 location
RECRUITINGPhase 2NCT06599658

COVID-19 Booster and IIV Schedule in Immunocompromised Hosts

The goal of this pragmatic embedded open-label, 2 x 2 factorial phase II randomized controlled trial is to evaluate strategies to improve COVID-19 booster and influenza vaccine...

Sponsor: McGill University Health Centre/Research Institute of the McGill University Health CentreEnrolling: 6603 locations

Frequently Asked Questions

There are currently 26 clinical trials for Rheumatoid Arthritis (RA), with 26 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Rheumatoid Arthritis (RA), review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 0 Phase 3 trials for Rheumatoid Arthritis (RA), representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice — always talk to your doctor about clinical trial participation.